Therapeutic Targets and Approaches to Manage Inflammation: Disappointing Past, Current Efforts and Faint Hopes

Dear Colleagues,

The scientific community has made several efforts in the past and until now to understand the fascinating and complex field of inflammation. Inflammation is a biological response to harmful stimuli but may also play a significant role in the pathogenesis of different diseases and sometimes may worsen their prognosis. In this context, different therapeutic approaches have been discovered to date but might also be responsible for side effects. For this reason, new treatments are needed to counteract inflammation, thus reducing the associated risks and side effects. The aim of this Special Issue is to collect past, current, and new insights regarding inflammation and its related molecular pathways in order to understand whether they could be useful as therapeutic targets: their modulation with specific drugs, also of natural origin, might contribute to the management of various chronic diseases. This Special Issue welcomes original research papers, short communications, and review articles that focus on inflammation and anti-inflammatory responses.

Dr. Natasha Irrera
Guest Editor

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• inflammation
• inflammatory pathways
• resolution of inflammation
• inflammasome
• molecular pathways
• anti-inflammatory response