Antimicrobial, Anti-biofilm and Anti-virulence Activities of Novel Compounds

Dear Colleagues,

The global prevalence of antibiotic-resistant bacteria has become a very significant concern. Natural products are increasingly investigated as they possess a large array of chemical compounds capable of exhibiting several biological activities such as potent antibacterial and antimicrobial properties.

Natural products also have the capability to affect distinct stages of biofilm formation, such as adhesion, motility, EPS maturation and targeting, as well as microbial virulence factors.

Natural compounds from plants, microbes and animals must be investigated to uncover their full potential as valuable sources to tackle persistent microbial infection.

The aim of this Special Issue is to collect important contributions in the field of natural and synthetic compounds via the investigation of novel antimicrobial, anti-biofilm and anti-virulence activities.

Research areas may include, but not limited to, the following:

• Study of natural compounds against microorganisms and ones that are multidrug-resistant;
• Study of anti-biofilm and anti-virulence activities of natural and/or semisynthetic/ synthetic products;
• Study of combinations of natural compounds and conventional antibiotics/antimicrobials;
• Study of an innovative delivery system to improve the bioavailability of natural compounds.

In this Special Issue, original research articles and reviews are welcome. I look forward to receiving your contributions.

Dr. Mara Di Giulio
Dr. Silvia Di Lodovico
Guest Editors

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• antimicrobial natural compound
• resistant strains
• mono- and polymicrobial biofilm
• synergisms
• antivirulence natural compounds