Molecular Metabolisms in Cartilage Health and Diseases 3.0

Dear Colleagues,

This Special Issue is a continuation of our previous Special Issue “Molecular Metabolisms in Cartilage Health and Diseases 2.0”.

Cartilage is a unique tissue as it is avascular and composed of only chondrocytes. Vascular invasion into the cartilage is a key step towards endochondral bone formation, as well as being involved in the pathogenesis of osteoarthritis. Because of the lack of blood flow, the regeneration or repair of damaged cartilage, such as those in osteoarthritis, is difficult to be achieved. The old and new problems in cartilage medicine are how to maintain cartilage homeostasis and how to regenerate or repair damaged cartilage. Many factors, such as growth factors, transcription factors, nutrition and its metabolites, extracellular matrix, and physical forces, are involved in cartilage growth, homeostasis, and regeneration. This Special Issue titled “Molecular Metabolisms in Cartilage Health and Diseases 3.0” focuses on the recent progress in the molecular aspects of cartilage metabolism and its regulation in normal and diseased cartilage.

Dr. Masaharu Takigawa
Guest Editor

Manuscript Submission Information

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• cartilage
• chondrocytes
• growth
• regeneration
• endochondral ossification
• arthritis
• joint
• growth factors
• mechanical stress
• nutrition