Advances in Metalloproteinase

Dear Colleagues,

Matrix metalloproteinases (MMPs) are a family of calcium-dependent zinc-containing endopeptidases that actively participate in the degradation of the extracellular matrix. These MMPs play pivotal roles in various pathological conditions, including cancer, inflammation, angiogenesis, atheroma, arthritis, and ulceration. Understanding the specific roles of MMPs in these processes is crucial for developing targeted therapeutic interventions. In some cases, MMP inhibitors are being explored as potential treatments for diseases where MMP activity is dysregulated.

This Special Issue, titled “Advances in Metalloproteinase”, delves into the intricate functions of MMPs, their substrate specificity, tissue inhibitors of metalloproteinases, and the activation of proMMP in disease contexts. We invite contributions in the form of original research and review articles focusing on the diverse aspects of MMPs.

Dr. Kyu-Yeon Han
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• matrix metalloproteinases (MMPs)
• substrate specificity
• pathological condition
• metalloproteinases inhibitors