Research on Molecular Chaperones: Role and Targeting in Health and Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Macromolecules".
Deadline for manuscript submissions: closed (17 December 2021) | Viewed by 14232
Special Issue Editors
Interests: molecular chaperones; heat shock proteins; post-translational modification; cell biology; tissue homeostasis; cancerogenesis; neurodegeneration; bioinformatics; anatomy
Special Issues, Collections and Topics in MDPI journals
Interests: extracellular vesicles; exosomes; miRNA; liquid biopsy; cancerogenesis; anatomy; molecular chaperones; heat shock proteins; extracellular chaperones
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to submit original articles to a Special Issue entitled “Research on molecular chaperones: role and targeting in health and disease”.
Molecular chaperones, most of which are heat shock proteins (HSPs), are part of phylogenetically related families and are essential in living cells. Molecular chaperones play a variety of roles, including assisting the folding of nascent polypeptides, supporting protein reparation or degradation, and driving protein translocation through membranes. Chaperones are induced after stress, which changes their localization and function. For example, they can be expressed in cell membranes or secreted extracellularly where they may interact with the immune system.
Due to the central role of molecular chaperones in different biological processes, their dysregulation or malfunction may cause several diseases. The goal of this Special Issue is to collect original research papers, reviews that focus on the role of molecular chaperones in human diseases and highlight the diagnostic and therapeutic applications of these chaperones.
Dr. Antonella Marino Gammazza
Dr. Celeste Caruso Bavisotto
Guest Editors
Keywords
- Molecular chaperones
- Lipidic chaperones
- Heat shock proteins
- Extracellular chaperones
- Extracellular vesicles
- Chronic diseases
- Tissue homeostasis
- Biomedicine
- Translational medicine
- Bioinformatics