Pharmaceutical Applications of Metal Complexes and Derived Materials
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: 20 September 2024 | Viewed by 1024
Special Issue Editor
Interests: basic chemistry of d and f-block elements; synthesis of bioactive ligands; metals in medicine; nuclear medicine; nanomaterials; new catalysts; biosensors; determination of crystal structures by single-crystal X-ray diffraction; mechanism of action of bioactive compounds
Special Issue Information
Dear Colleagues,
In recent years, Medicinal Inorganic Chemistry has demonstrated remarkable capacity in the development of metal complexes and related materials with innumerous pharmaceutical applications, encompassing therapeutic, diagnostic and theranostic purposes. The coordination of biologically active organic molecules and preparation of metallo-bionanomaterials has been used as a strategy to circumvent many of the difficulties associated with current chemotherapies, such as high toxicity, lack of activity during the chronic phase and cellular and microbial resistances. For the precise diagnosis of cancer and other diseases, considerable efforts have been made to develop more effective therapies, molecular imaging technologies and electronic devices which are based on the singular properties of metal complexes, such as the luminescent and magnetic, participation in redox processes and radiolabeling using metal radioisotopes.
In this Special Issue, all contributions (original or review) on novel biologically active coordination compounds and related materials employed as pharmacological tools, including reports on their synthesis and characterization; preparation of biosensors; radiolabeling of ligands; biochemical/pharmacological evaluation and incorporation in drug delivery systems; as well as investigations of their biological targets, are welcome. Studies concerning known compounds, comprising analytical and computational investigations, are also encouraged provided there is a clear benefit to the field of Medicinal Chemistry.
Prof. Dr. Pedro Ivo da Silva Maia
Guest Editor
Manuscript Submission Information
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Keywords
- metallodrugs
- metal complexes in cancer treatment
- metal complexes as antimicrobial agents
- delivery systems containing metal complexes
- metal complexes in photodynamic therapy
- metal complexes in biosensors
- metal complexes as biomarkers
- radiopharmaceuticals
- computational studies in metallodrugs development
- mechanism of action of bioactive metal complexes
