Alternative Model-Based Translational Drug Development

Dear Colleagues,

The quest for effective and safe drug delivery systems has been a driving force in pharmaceutical research. Delivering medications efficiently and accurately to their intended targets is crucial for maximizing therapeutic outcomes while minimizing adverse effects. Recently, there has been a growing emphasis on exploring innovative and alternative models to revolutionize drug delivery. Traditional approaches to drug delivery have often faced challenges, such as limited efficacy, poor bioavailability, and off-target effects. These limitations have prompted researchers and scientists to explore new avenues for drug delivery that can overcome these hurdles and provide improved therapeutic options for patients. One area that has gained significant attention is the intersection between drug formulation and translational medicine. Translational medicine bridges the gap between laboratory discoveries and their practical application in clinical settings. By incorporating translational medicine principles into drug formulation, researchers aim to enhance the development and delivery of pharmaceutical formulations, ultimately leading to better patient outcomes.

This Special Issue aims to shed light on the latest advancements in alternative drug delivery models and their potential implications for translational medicine. We will explore how these innovative approaches can improve the efficiency of drug formulations, promote personalized medicine, and address the specific needs of individual patients. By highlighting the importance of this research area, we aim to inspire further exploration and collaboration among scientists, clinicians, and pharmaceutical experts. Ultimately, our collective efforts in advancing drug delivery systems have the potential to transform the field of medicine, revolutionize treatment approaches, and enhance patient care.

In this Special Issue, original research articles and reviews are welcome. Research areas may include, but are not limited to, the following:

• Recent developments in nanotechnology-based drug delivery systems, including nanoparticles, liposomes, and micelles.
• Alternative models for drug delivery research, such as organoids, microfluidic systems, and computational modeling.
• Bioengineering strategies for personalized medicine, such as 3D printing of drug delivery devices and organs-on-chips.
• Development of patient-specific drug delivery systems, considering factors like genetic variations and disease-specific characteristics.
• Design and evaluation of preclinical models that better mimic human physiology and predict clinical outcomes.
• Development of novel targeting agents and strategies to improve drug accumulation at specific disease sites.
• Case studies on the clinical application of targeted drug delivery systems, highlighting their efficacy and potential impact on patient outcomes.
• Application of alternative models in studying drug transport, absorption, and distribution.

We look forward to receiving your contributions. 

Dr. Francislaine Aparecida Dos Reis Lívero
Dr. Arquimedes Gasparotto Junior
Guest Editors

Manuscript Submission Information

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• pharmaceutical preparations
• drug compounding
• drug delivery systems
• translation medicine
• alternative models
• preclinical studies