Nano-Based Drug Delivery System: Recent Developments and Future Prospects

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 30 April 2024 | Viewed by 1309

Special Issue Editors


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Guest Editor
Drugs and Medicines Department, Universidade Estadual Paulista, Araraquara, São Paulo 14800-903, Brazil
Interests: nanotechnology; emulsified nanostructured systems; nanoparticles; drug formulation

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Guest Editor
Drugs and Medicines Department, Universidade Estadual Paulista, Araraquara, São Paulo 14800-903, Brazil
Interests: nanotechnology; bioadhesive nanostructure systems; nano-biointerface; quality control

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Guest Editor
Pharmacy Department, Universidade Federal do Rio Grande do Norte, Natal 59012-570, Brazil
Interests: microemulsions; nanotechnology; drug delivery
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Drugs and Medicines Department, Universidade Estadual Paulista, Araraquara, São Paulo 14800-903, Brazil
Interests: nanotechnology; drug delivery; nanocarriers development

Special Issue Information

Dear Colleagues,

Nanotechnology applied to therapeutics has been widely updated, promoting adequate alternatives to improve the therapeutic arsenal in numerous disorders and diseases. Many drugs have been targeted by universities, industries and research centres in order to improve their biopharmaceutical, pharmacokinetic, physicochemical and chemical characteristics. In addition, the toxicity and side effects, as well as the low specificity of the target sites, have challenged researchers around the world to invest in nanotechnology, providing updates, including unique and numerous nanotechnology-based drug delivery systems in the world scenario. This Special Issue is dedicated to the publication of original articles and reviews focused on the development of nanostructured systems for drug delivery (synthetic, natural and mineral source); preformulation studies, evaluation of in vitro and in vivo biological activity, toxicity, genotoxicity, stability, degradation and others.

Prof. Dr. Lucas Amaral-Machado
Prof. Dr. Leonardo Miziara Barboza Ferreira
Prof. Dr. Eryvaldo Sócrates Tabosa Do Egito
Dr. Jonatas Lobato Duarte
Guest Editors

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Keywords

  • nanostructured carriers
  • microemulsions
  • nanoemulsions
  • nanoparticles
  • liposomes
  • nanogels
  • dendrimers

Published Papers (1 paper)

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Review

33 pages, 8768 KiB  
Review
Recent Developments in CaCO3 Nano-Drug Delivery Systems: Advancing Biomedicine in Tumor Diagnosis and Treatment
by Chenteng Lin, Muhammad Akhtar, Yingjie Li, Min Ji and Rongqin Huang
Pharmaceutics 2024, 16(2), 275; https://0-doi-org.brum.beds.ac.uk/10.3390/pharmaceutics16020275 - 15 Feb 2024
Viewed by 981
Abstract
Calcium carbonate (CaCO3), a natural common inorganic material with good biocompatibility, low toxicity, pH sensitivity, and low cost, has a widespread use in the pharmaceutical and chemical industries. In recent years, an increasing number of CaCO3-based nano-drug delivery systems [...] Read more.
Calcium carbonate (CaCO3), a natural common inorganic material with good biocompatibility, low toxicity, pH sensitivity, and low cost, has a widespread use in the pharmaceutical and chemical industries. In recent years, an increasing number of CaCO3-based nano-drug delivery systems have been developed. CaCO3 as a drug carrier and the utilization of CaCO3 as an efficient Ca2+ and CO2 donor have played a critical role in tumor diagnosis and treatment and have been explored in increasing depth and breadth. Starting from the CaCO3-based nano-drug delivery system, this paper systematically reviews the preparation of CaCO3 nanoparticles and the mechanisms of CaCO3-based therapeutic effects in the internal and external tumor environments and summarizes the latest advances in the application of CaCO3-based nano-drug delivery systems in tumor therapy. In view of the good biocompatibility and in vivo therapeutic mechanisms, they are expected to become an advancing biomedicine in the field of tumor diagnosis and treatment. Full article
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