Interference of Bacterial Signaling as a New Strategy for Treatment of AMR Pathogens
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 17345
Special Issue Editor
Interests: antimicrobial resistance (AMR); biofilm; environmental response; molecular genetics; bacterial pathogenicity; infection control
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The increase and spread of AMR (antimicrobial resistance) pathogens with a shortage of new antimicrobial agents are critical issues. Therefore, new approaches are needed for the treatment of infections caused by these pathogens. Bacteria use particular signal molecules when they encounter environmental changes or contact with other bacterial members, then alter their gene expression. This manner termed “bacterial signaling” has been observed in many species including animal and plant pathogens. There is increasing evidence that it is closely associated with bacterial virulence, and characterized as virulence determinants to establish infections. Thus, bacterial signaling is proposed as a potential target for the development of antimicrobial agents. In the past two decades, many attempts to interfere with bacterial signaling are have been conducted with great interest. This Special Issue will provide updates on topics related to bacterial signaling interference and conquering refractory AMR infections. We invite manuscripts on studies that include the following topics:
- Chemical compounds, proteins, or nucleic acids targetting bacterial signaling and their molecular mechanisms
- Innovative chemotherapy applications and the use of inhibitors of bacterial signaling (such as combination chemotherapy)
Dr. Hidetada Hirakawa
Guest Editor
Manuscript Submission Information
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Keywords
- antimicrobial resistance
- bacterial signal
- quorum sensing
- biofilm
- virulence
- combination chemotherapy