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Biomedicines
Special Issues
Neurogenesis and Neurological Disorders
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Neurogenesis and Neurological Disorders

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 1400

Special Issue Editor

Prof. Ujendra Kumar

E-Mail Website
Guest Editor
Faculty of Pharmaceutical sciences, University of British Columbia, Vancouver, Canada
Interests: Neuroscience, GPCR, breast cancer and Pharmacology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Neurogenesis, the process involve in generation of new neurons occurs during embryonic development has been challenged and growing evidence support occurrence of neurogenesis in adult brain. Neurogenesis play crucial role in brain functions. The concept that neurogenesis might play important role in neurological and neuropsychological diseases and studies supporting the generation of new neurons throughout the life specifically in brain region hippocampus involve in cognitive and memory function are of specific interest. Importantly, neurogenesis explores new way to look psychological and neurological disorders as well as in the process of addiction. Biomedicines seeking manuscripts for special issue on ‘Neurogenesis and neurological disorders’ to fill a literature gap on this most advance and interesting topic. As a Guest Editor of this special issue, I invite you to submit a manuscript.

Dr. Ujendra Kumar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Review

13 pages, 611 KiB  
Review
Targeting Neurogenesis in Seeking Novel Treatments for Ischemic Stroke
by Takayuki Nagase, Kyohei Kin and Takao Yasuhara
Biomedicines 2023, 11(10), 2773; https://0-doi-org.brum.beds.ac.uk/10.3390/biomedicines11102773 - 13 Oct 2023
Cited by 1 | Viewed by 969
Abstract
The interruption of cerebral blood flow leads to ischemic cell death and results in ischemic stroke. Although ischemic stroke is one of the most important causes of long-term disability and mortality, limited treatments are available for functional recovery. Therefore, extensive research has been [...] Read more.
The interruption of cerebral blood flow leads to ischemic cell death and results in ischemic stroke. Although ischemic stroke is one of the most important causes of long-term disability and mortality, limited treatments are available for functional recovery. Therefore, extensive research has been conducted to identify novel treatments. Neurogenesis is regarded as a fundamental mechanism of neural plasticity. Therefore, therapeutic strategies targeting neurogenesis are thought to be promising. Basic research has found that therapeutic intervention including cell therapy, rehabilitation, and pharmacotherapy increased neurogenesis and was accompanied by functional recovery after ischemic stroke. In this review, we consolidated the current knowledge of the relationship between neurogenesis and treatment for ischemic stroke. It revealed that many treatments for ischemic stroke, including clinical and preclinical ones, have enhanced brain repair and functional recovery post-stroke along with neurogenesis. However, the intricate mechanisms of neurogenesis and its impact on stroke recovery remain areas of extensive research, with numerous factors and pathways involved. Understanding neurogenesis will lead to more effective stroke treatments, benefiting not only stroke patients but also those with other neurological disorders. Further research is essential to bridge the gap between preclinical discoveries and clinical implementation. Full article
(This article belongs to the Special Issue Neurogenesis and Neurological Disorders)
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