Extracellular Vesicles in Phylogeny 2.0

Dear Colleagues,

Extracellular vesicles are 30–1000 nm lipid vesicles (also commonly called exosomes and microvesicles) which are released from most cells and participate in cellular communication in health and disease via transport of a genetic and protein cargo. EVs can be isolated from a range of body fluids and are therefore also valuable health- and pathology-related biomarkers. A large body of work has been carried out on the functions of EVs in a range of pathological processes and in normal physiology, while relatively less is known about the diversity of EVs and EV-mediated roles across phylogeny.

This Special Issue aims to collect state-of-the-art primary research studies and review articles from international experts and diverse leading groups in the EV field to update our current understanding of EVs in diverse taxa from bacteria to mammals, including humans. The focus will be on elucidating the multifaceted roles of EVs, including their potential for biomarker discovery, veterinary research, wildlife research and conservation, and research in bacterial communication, zoonotic disease, infectious disease, and host–pathogen interactions. Research on EVs using comparative animal models to study human pathologies as well as unusual metabolic and immunological traits that can inform longevity, disease resistance, and health, are also welcome.

Prof. Dr. Sigrun Lange
Guest Editor

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• extracellular vesicles
• phylogeny
• immunology
• infectious disease
• metabolism
• longevity
• disease resistance
• cancer resistance
• antibiotic resistance
• zoonotic disease
• host-pathogen interactions
• pathology
• veterinary research
• wildlife conservation
• comparative animal models
• biomarkers