Blood-Brain Barrier in Neuroinflammation and Neurological Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: 20 September 2024 | Viewed by 658
Special Issue Editor
Special Issue Information
Dear Colleagues,
The blood-brain barrier (BBB) plays a role as a structural and functional barrier that restricts the passage of soluble mediators and leukocytes from the blood to the central nervous system (CNS). Breakdown of the BBB is the key feature in several neuroimmunological diseases, including multiple sclerosis, neuromyelitis optica, collagen disease and autoimmune encephalitis. In addition, dysfunction of BBB is also noted in various neurological diseases, including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, trauma, diabetes, hypertension, cerebral small vessel disease and neuropathic pain. However, optimal treatment targeting the BBB has not been yet developed.
This Special Issue aims to focus on both basic molecular science and translational research on the blood-brain barrier in neuroinflammation and neurological diseases. We invite submissions of manuscripts related to the establishment of new BBB in vitro/in vivo models, pathological observation of BBB, or new diagnostic biomarkers of BBB breakdown in these diseases, the blood-nerve barrier and blood–CSF barrier. Review articles on the BBB highlighting the pathomechanisms and treatment strategies in these diseases will also be accepted.
Dr. Fumitaka Shimizu
Guest Editor
Manuscript Submission Information
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Keywords
- blood-brain barrier
- in vitro model
- in vivo model
- pathology
- blood–spinal cord barrier
- blood–CSF barrier
- blood–nerve barrier
- multiple sclerosis
- neuromyelitis optica
- Alzheimer’s disease
- Parkinson’s disease
- collagen disease
- autoimmune encephalitis
- amyotrophic lateral sclerosis
- trauma
- diabetes
- cerebral small vessel disease
- neuropathic pain
- autoimmune neuropathy
