Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.8
5.6
Journals
IJMS
Special Issues
Molecular Research in Cancer Radiotherapy
ijms-logo
Submit to Special Issue Submit Abstract to Special Issue Review for IJMS Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Molecular Research in Cancer Radiotherapy

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Oncology".

Deadline for manuscript submissions: 15 May 2024 | Viewed by 1185

Special Issue Editor

Dr. Dong Soo Lee

E-Mail Website
Guest Editor
Associate Professor, Department of Radiation Oncology, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea
Interests: clinical radiation therapy; radiation biology; radiation physics

Special Issue Information

Dear Colleagues,

The molecular and technological aspects of the field of radiation therapy have grown rapidly. Several factors, including the patient, radiation biological, and radiation physics components, can influence the outcomes of radiotherapy for cancer. Recent advances in novel pharmaceuticals, molecular technologies, and outcome prediction models have increased the significance of molecular research in cancer. This special issue emphasizes the most recent findings of molecular research in radiotherapy for cancer, with a focus on radiotherapy-related molecular alterations, biomarkers, and mechanisms. We invite submissions of research articles and reviews addressing contemporary molecular research in cancer radiotherapy.

Dr. Dong Soo Lee
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomarkers
  • biochemistry
  • cancer
  • epigenetics
  • genes: genomics: metabolomics
  • microbiome
  • molecules
  • proteomics
  • radiotherapy
  • serum
  • transcriptomics
 

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

19 pages, 927 KiB  
Review
Modulation of CD8+ T Cell Responses by Radiotherapy—Current Evidence and Rationale for Combination with Immune Checkpoint Inhibitors
by Seung Hyuck Jeon, Changhoon Song, Keun-Yong Eom, In Ah Kim and Jae-Sung Kim
Int. J. Mol. Sci. 2023, 24(23), 16691; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms242316691 - 24 Nov 2023
Cited by 1 | Viewed by 884
Abstract
Radiotherapy for cancer has been known to affect the responses of immune cells, especially those of CD8+ T cells that play a pivotal role in anti-tumor immunity. Clinical success of immune checkpoint inhibitors led to an increasing interest in the ability of [...] Read more.
Radiotherapy for cancer has been known to affect the responses of immune cells, especially those of CD8+ T cells that play a pivotal role in anti-tumor immunity. Clinical success of immune checkpoint inhibitors led to an increasing interest in the ability of radiation to modulate CD8+ T cell responses. Recent studies that carefully analyzed CD8+ T cell responses following radiotherapy suggest the beneficial roles of radiotherapy on anti-tumor immunity. In addition, numerous clinical trials to evaluate the efficacy of combining radiotherapy with immune checkpoint inhibitors are currently undergoing. In this review, we summarize the current status of knowledge regarding the changes in CD8+ T cells following radiotherapy from various preclinical and clinical studies. Furthermore, key biological mechanisms that underlie such modulation, including both direct and indirect effects, are described. Lastly, we discuss the current evidence and essential considerations for harnessing radiotherapy as a combination partner for immune checkpoint inhibitors. Full article
(This article belongs to the Special Issue Molecular Research in Cancer Radiotherapy)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop