Special Issue "Cholinergic Signaling in Human Health and Diseases 2.0"
Deadline for manuscript submissions: 20 October 2021.
Interests: intestinal organoid; stem cell; signaling; non-neuronal acetylcholine; acetylcholine receptor
Special Issues and Collections in MDPI journals
This Special Issue is the continuation of our previous Special Issue "Cholinergic Signaling in Human Health and Diseases".
It is now well-established that acetylcholine (ACh) and its receptors (nicotinic and muscarinic receptors (n- and mAChRs)) as important constituents of the cholinergic system are ubiquitous molecules in life. Other components of the cholinergic system (choline acetyltransferase (ChAT), choline transporter (ChT), and acetylcholinesterase (AChE)) have also been demonstrated in mammalian non-neuronal cells, including those of humans. The traditional view of ACh regards it as a neurotransmitter. In addition to neurotransmission, ACh plays important roles in various aspects of cell biology and homeostasis outside of the nervous system. ACh is actually synthesized by all live cells and plays an intermediary role in the interactions of non-neuronal cells with the external environment, endocrine hormones, growth factors, cytokines, and the central nervous system. Thus, cholinergic signaling in non-neuronal cells is comparable to neuronal cholinergic signaling. In addition to improving our understanding of the structure and function of the cholinergic system, significant progress has also been made in elucidating the roles of neuronal and non-neuronal ACh in the pathogenesis and treatment of human disease. This Issue will explore new insights into how cholinergic signaling functions in mammals, how its roles contribute to protecting the body from disease, and how the molecules can be manipulated to treat disease.
Dr. Toshio Takahashi
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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- immune cell
- stem cell
- acetylcholine (ACh)
- non-neuronal ACh
- acetylcholine receptor
- acetylcholine receptor to muscarinic ACh receptor
- nicotinic ACh receptor