Dear Colleagues,

In many countries around the world, the number of chronic and complex diseases is increasing as the population continues to age. In the development of foods, cosmetics, and pharmaceutical materials that can prevent and treat these diseases, natural products are expected to have fewer side effects than synthetic compounds, and thus are being studied a lot. Furthermore, since it has been widely used in traditional medicine since ancient times, it is highly expandable if a scientific basis is established. Antioxidant activity has been suggested as a mechanism of action of these natural products. However, it is difficult to explain the mechanism of action only by the antioxidant activity in terms of low intracellular concentrations and different effects of each substance. As a mechanism of action of these natural substances, it has been reported that they directly bind to kinases that play an important role in the signal transduction system to show an effect. This issue will explore new insights into noble targets of natural products.

Dr. Jong-Eun Kim
Guest Editor

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• natural product
• kinase
• direct target