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Special Issue "Neurodegenerative Diseases: From Molecular Basis to Therapy"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editors

Prof. Dr. Marcello Ciaccio
E-Mail Website
Guest Editor
Department of Biomedicine, Neurosciences and Advanced Diagnostics, Institute of Clinical Biochemistry, Clinical Molecular Medicine and Laboratory Medicine, University of Palermo, Palermo, Italy
Interests: multiple sclerosis; neurodegeneration; dementia; vitamin D; cerebrospinal fluid biomarkers; molecular and cellular neuroscience
Special Issues and Collections in MDPI journals
Dr. Luisa Agnello
E-Mail Website
Guest Editor
Institute of Clinical Biochemistry, Clinical Molecular Medicine and Laboratory Medicine, Department of Biomedicine, Neurosciences and Advanced Diagnostics, University of Palermo, Palermo, Italy
Interests: multiple sclerosis; biomarkers; vitamin D

Special Issue Information

Dear Colleagues,

Neurodegenerative diseases (NDs) are a heterogeneous group of complex diseases, characterized by neuronal loss and progressive degeneration of different areas of the nervous system. NDs represent a major health problem worldwide, with an increasing incidence rate. Although the exact pathogenesis of NDs remains unclear, a complex interaction between genetic, epigenetic and environmental factors has been proposed. To date, no effective therapeutics have been developed to slow, halt or prevent any NDs. Thus, information on the molecular mechanisms underlying the pathogenesis of NDs is strongly sought after.

The aim of the current Special Issue is to describe the advances in the field of NDs, including Alzheimer’s disease, multiple sclerosis, amyotrophic lateral sclerosis and Parkinson’s disease, with a focus on the underlying pathobiological mechanisms.

We would like to invite you to submit original research articles and reviews on, but not limited to, new findings on molecular key players, pathomechanisms, risk factors, biomarkers and therapeutic targets of NDs.

Prof. Dr. Marcello Ciaccio
Dr. Luisa Agnello
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • genetic
  • biomarkers
  • Alzheimer’s disease
  • multiple sclerosis
  • amyotrophic lateral sclerosis
  • neurodegenerative diseases

Published Papers

This special issue is now open for submission.
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