Orphan Drugs
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pharmacology".
Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 6769
Special Issue Editor
Interests: synthesis and biological studies on anti-inflammatory and antioxidant agents, on inhibitors of enzymes implicated in the inflammation and in the coagulation process in general; correlation of inflammation with cancer; neurodegeneration; antioxidant activity; theoretical and experimental calculation of physicochemical parameters implicated in biological response; use of computational chemistry in drug design as well as bioactive compounds of natural origin, e.g., essential oils
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are all familiar with the great problem of rare diseases and of their treatment and cure. “Orphan viruses”, for example, which are not linked to a recognized disease, such as hepatitis G, as well as genes, receptors, and enzymes, lead to orphan diseases, which imply two separate but related concepts: (a) diseases that are neglected by doctors and (b) diseases that affect a small number of people. Thus, the term “orphan drugs” describes rare medicinal products intended for diagnosis, prevention or treatment of life-threatening or very serious rare diseases or disorders. In the last 30 years, efforts have been made to encourage companies to develop orphan drugs.
This Topical Collection, “Orphan Drugs”, of the International Journal of Molecular Sciences will comprise a selection of research papers and reviews offering knowledge on the development of orphan drugs, rare diseases for which research was successful, rare diseases and their treatment with well-known orphan drugs, new entities inserted in clinical applications, and future perspectives.
Moreover, in vitro and in vivo studies will provide a possible high impact in the development of orphan-drug-based strategies and in the identification of the key biological regulation processes that remain uncovered.
Prof. Dr. Dimitra Hadjipavlou-Litina
Guest Editor
Manuscript Submission Information
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Keywords
- Orphan drugs
- Orphan diseases
- Rare diseases
- Neglected diseases
- Orphan viruses
- Development of orphan drugs
- Synthesis
- Design
- Clinical studies
- Biological evaluation
