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Special Issue "Probiotics in Human Health and Diseases"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editor

Prof. Dr. Satya Prakash
E-Mail Website
Guest Editor
Faculty of Medicine, McGill University, Montréal, QC, Canada
Interests: bioengineering; artificial cell; biomaterial; drug delivery; microbiome; probiotics; regenerative medicine; cell therapy; health food; GI model; stem cell; heart health; medical device

Special Issue Information

Dear Colleagues,

Probiotics have shown significant human health benefits for the majority of human diseases. Probiotics are predicted to be useful in the prevention and therapy of diseases such as diabetes, obesity, cancer, cardiovascular dysfunctions, inflammatory bowel diseases, neurological disorders, and other chronic diseases. Significant advancements have been made in microbiome and probiotic research. These include the development of mechanism-based probiotics, novel delivery methods such as micro/nanocapsules and powders, the design of probiotic formulations in food and drinks, and other innovations.

This Special Issue will cover the state of the art of research in probiotics’ role in human health and disease. Both original research articles and reviews on this subject are welcome.

Prof. Dr. Satya Prakash
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • Probiotics
  • Microbiome
  • Human Health
  • Live Bacteria
  • Biomedicine
  • Diabetes
  • Obesity
  • Cancers
  • Cardiovascular diseases
  • Inflammatory Bowel Diseases
  • Neurological Disorders
  • Chronic Diseases

Published Papers (1 paper)

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Probiotics, Photobiomodulation, and Disease Management: Controversies and Challenges
Int. J. Mol. Sci. 2021, 22(9), 4942; https://0-doi-org.brum.beds.ac.uk/10.3390/ijms22094942 - 06 May 2021
Cited by 2 | Viewed by 1626
In recent decades, researchers around the world have been studying intensively how micro-organisms that are present inside living organisms could affect the main processes of life, namely health and pathological conditions of mind or body. They discovered a relationship between the whole microbial [...] Read more.
In recent decades, researchers around the world have been studying intensively how micro-organisms that are present inside living organisms could affect the main processes of life, namely health and pathological conditions of mind or body. They discovered a relationship between the whole microbial colonization and the initiation and development of different medical disorders. Besides already known probiotics, novel products such as postbiotics and paraprobiotics have been developed in recent years to create new non-viable micro-organisms or bacterial-free extracts, which can provide benefits to the host with additional bioactivity to probiotics, but without the risk of side effects. The best alternatives in the use of probiotics and postbiotics to maintain the health of the intestinal microbiota and to prevent the attachment of pathogens to children and adults are highlighted and discussed as controversies and challenges. Updated knowledge of the molecular and cellular mechanisms involved in the balance between microbiota and immune system for the introspection on the gut–lung–brain axis could reveal the latest benefits and perspectives of applied photobiomics for health. Multiple interconditioning between photobiomodulation (PBM), probiotics, and the human microbiota, their effects on the human body, and their implications for the management of viral infectious diseases is essential. Coupled complex PBM and probiotic interventions can control the microbiome, improve the activity of the immune system, and save the lives of people with immune imbalances. There is an urgent need to seek and develop innovative treatments to successfully interact with the microbiota and the human immune system in the coronavirus crisis. In the near future, photobiomics and metabolomics should be applied innovatively in the SARS-CoV-2 crisis (to study and design new therapies for COVID-19 immediately), to discover how bacteria can help us through adequate energy biostimulation to combat this pandemic, so that we can find the key to the hidden code of communication between RNA viruses, bacteria, and our body. Full article
(This article belongs to the Special Issue Probiotics in Human Health and Diseases)
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