Dear Colleagues,

We cordially invite you to submit experimental papers, review articles, or commentaries for an upcoming issue of IJMS, which Marc and I are supporting as guest editors.

There is no doubt, essential cellular processes are crucially dependent on correct Ca²⁺ signaling through Ca²⁺ release-activated Ca²⁺ (CRAC) channels. In the past decade, important advances have been made in the characterization of the CRAC channel key players, STIM1 and Orai1; their impact on human diseases; and accessory proteins supporting the Ca²⁺ signaling cascade. Much effort has gone into understanding the processes underlying physiological Ca²⁺ signaling.

This Special Issue of IJMS (“STIMulating Ca²⁺ Homeostasis”) will cover a selection of novel research and review articles in the field of Ca²⁺ signaling through CRAC channels. It will focus on Ca²⁺ homeostasis within cells; store-operated Ca²⁺ entry; CRAC channel proteins; STIM/Orai proteins including their isoforms, their structure/activation/interaction, and gating, accessory proteins; diseases related to altered Ca²⁺ homeostasis; MD simulations on Ca²⁺ signaling proteins; and the use of CRISPR/Cas9 techniques in this field.

Dr. Irene Frischauf
Dr. Marc Fahrner
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.