Dear Colleagues,

Integrative oncology, a holistic and patient-centered approach, may help to support the health of patients with cancer, as demonstrated by multiple studies that have shown the benefits and potential of complementary health therapies in addition to conventional cancer care. For these reasons, several scientific associations are now focused on integrative oncology with the aim of changing the paradigm of cancer from 'incurable' to 'sustainable, thus offering new therapeutic options.

In this Special Issue, we attempt to reflect part of the research activity in the field of integrative oncology. The focus will be placed on those findings relevant to clinical cancer research and supported by cellular and molecular in vitro studies. Moreover, a growing number of proofs highlights the strong connection between the human intestinal microbiota and the etiology of colorectal cancer, as well as recent studies are focused on the mechanisms at the basis of the effects of natural products, used to manage the adverse reactions in cancer patients. Hence, the main subjects of this Special Issue will comprise these emergent topics, underlining the role of diet, immune response and epigenetic in cancer therapy and prevention.

The Special Issue will also include articles from the 2nd WORLD CONGRESS OF INTEGRATIVE MEDICINE AND HEALTH CONGRESS (https://icimcongress.org/), which will be held in Rome, Italy, 20–23 September 2023. Therefore, articles on Integrative Medicine, even if not strictly linked to the cancer topic, will also be taken into consideration.

Prof. Dr. Carla Fiorentini
Dr. Maria Pia Fuggetta
Guest Editors

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• integrative oncology
• cancer therapy
• cancer prevention
• natural products
• microbiota
• epigenetics on cancer