Special Issue "Thiophilic Metals: An Ancient Love for Sulfur at the Heart of Biochemistry"
Deadline for manuscript submissions: 31 July 2021.
Interests: bioorganic chemistry; catalytic sensor/effector agents; epistemology; intracellular diagnostics; nanotechnology; natural products; reactive sulfur and selenium species; redox regulation via the cellular thiolstat
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Thiophilic metal ions, such as zinc, copper, iron, and molybdenum, are present in virtually all organisms where they fulfil a multitude of functions and often bind to sulfur as their ligands. The resulting medley of metal binding and exchange on the one side and redox activity of some of these metals and sulfur ligands on the other leads to a truly complex chemistry that is reflected in their biochemistry. This Special Issue will consider the current state of such thiophilic metal ions in biology, with a focus on their chemistry, trafficking, exchange, biological actions, and redox control. Some of this bioinorganic chemistry is established, other aspects are still speculative and in need of investigation. This includes evolutionary aspects; sulfur cycles controlling such thiophilic metals in the geosphere and biosphere; and selenophilic metals and interactions with other chalcogens, such as tellurium and polonium. This Special Issue is dedicated to Bert L. Vallee, the discoverer of the metallothioneins, on occasion of his 100th birthday in 2019.
Prof. Dr. Claus Jacob
Prof. Dr. Wolfgang Maret
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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