ijms-logo

Journal Browser

Journal Browser

Preparation and Nutritional Regulation of Biological Components

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 1626

Special Issue Editors

Center for Mitochondria and Healthy Aging, College of Life Sciences, Yantai University, Yantai 264005, China
Interests: peptides; minerals; bioaviabiltiy; osteoporosis; antioxidan; aquogel

E-Mail Website
Guest Editor
Beijing Key Laboratory of Functional Food from Plant Resources, College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China
Interests: starch; functional foods; gels

Special Issue Information

Dear Colleagues,

Food processing technology, including fermentation, extraction, encapsulation, enzymolysis, improve the specific nutritional or functional components of food ingredients while generating new ingredients. Currently, with the transformation of medical treatment mode in modern society, the concept of great health is deeply rooted in people's hearts. Especially during the COVID-19 epidemic, bioactive components have become a hot topic due to potential health benefits. It is necessary to know the improvement of various disease states (including cancer, cardiovascular disease, diabetes, osteoporosis, hyperlipidemia, ect) by bioactive ingredients, so as to obtain a good scientific basis to confirm the approval of health claims.This Special Issue, “Preparation and Nutritional Regulation of Biological Components”, aims to cover all aspects of bioactive components research in relation to health promotion. In particular, this Special Issue stresses current research trends about bioactive components, including production and purification of bioactive components from new sources; relationships between structure and function; mechanisms of action; in vitro and in vivo assays for the evaluation of bioactivity; physiological evidence to support health benefits; and bioavailability of bioactive components. Additionally, functional foods or health care products with biological activity will also be considered.

Dr. Jing Gan
Prof. Dr. Yongqiang Cheng
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • human health
  • bioactive peptides
  • polyphenol
  • nutrient
  • ln vitro and in vivo assays
  • identification and characterization 

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 4709 KiB  
Article
Elsholtzia bodinieri Vaniot Ameliorated Acute Lung Injury by NQO1, BCL2 and PTGS2 In Silico and In Vitro Analyses
by Jin Sun, Xiaoqian Jiang, Yuxu Chen, Shancheng Guo, Zhiye Zhao, Jianxin Cao, Yaping Liu, Guiguang Cheng, Ye Li and Lei Tian
Int. J. Mol. Sci. 2022, 23(24), 15651; https://doi.org/10.3390/ijms232415651 - 09 Dec 2022
Cited by 2 | Viewed by 1232
Abstract
Acute lung injury (ALI) is a clinical respiratory disease caused by various factors, which lacks effective pharmacotherapy to reduce the mortality rate. Elsholtzia bodinieri Vaniot is an annual herbaceous plant used as a traditional herbal tea and folk medicine. Here we used bioinformatic [...] Read more.
Acute lung injury (ALI) is a clinical respiratory disease caused by various factors, which lacks effective pharmacotherapy to reduce the mortality rate. Elsholtzia bodinieri Vaniot is an annual herbaceous plant used as a traditional herbal tea and folk medicine. Here we used bioinformatic databases and software to explore and analyze the potential key genes in ALI regulated by E. bodinieri Vaniot, including B cell leukemia/lymphoma 2 (Bcl2), prostaglandin-endoperoxide synthase 2 (Ptgs2) and NAD(P)H dehydrogenase, quinone 1 (Nqo1). In an inflammatory cells model, we verified bioinformatics results, and further mechanistic analysis showed that methanol extract of E. bodinieri Vaniot (EBE) could alleviate oxidative stress by upregulating the expression of NQO1, suppress pyroptosis by upregulating the expression of BCL2, and attenuate inflammation by downregulating the expression of PTGS2. In sum, our results demonstrated that EBE treatment could alleviate oxidative stress, suppress pyroptosis and attenuate inflammation by regulating NQO1, BCL2 and PTGS2 in a cells model, and E. bodinieri Vaniot might be a promising source for functional food or as a therapeutic agent. Full article
(This article belongs to the Special Issue Preparation and Nutritional Regulation of Biological Components)
Show Figures

Figure 1

Back to TopTop