Topical Collection "Antifungal Compounds"
Interests: metal complexes; biological properties; sulfur containing ligands; thiosemicarbazones; anticancer compounds; antiviral compounds; metal-based antibiotics; antimycotic compounds; antioxidants; apoptosis; X-ray diffraction; inorganic synthesis; topoisomerase IIA; phototherapy; nanoparticles
A fungicide is any agent that can prevent, moderate, repel or even kill fungi. Being widely applied as a treatment against both human and plant pathogens as well as a preservative additive for food commodities or for the conservation of porous building materials in monuments, fungicides have undoubtedly become a feature that the environment has to cope with. The mode of action of antifungals is closely related to specific metabolic pathways; however, despite certain similarities between fungi and animals, such mechanisms are frequently difficult to elucidate. Additionally, due to the increase in occurrences of resistance, the beneficial role of known fungicides is rapidly declining, which poses a serious threat to human health and agriculture and creates a vulnerability to fungi in both plants and animals. Today, since new strategies are required to face new problems, it is necessary more than ever to promote investigations focused on the molecular mechanisms surrounding the biological activity of fungicide/fungistatic compounds in order to provide crucial insights on fungicides that could potentially be strategic for their implementation.
In this Topical Collection, the most recent scientific advances on the molecular mechanisms behind fungicides’ biological activity, use, physical state, pathophysiological effects and sources will be presented. Research manuscripts and review articles focused on the cellular/molecular mechanisms of fungicide-promoted toxicity in target and non-target organisms, biodegradation, biotransformation and bioaccumulation, innovative formulation technologies, lead projects aimed at the development of new generation antifungal bioactives or overcoming fungicide resistance will be considered.
Prof. Dr. Giorgio Pelosi
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Antifungal compounds
- Fungal pathogen drug resistance
- Fungal growth inhibitors
- Fungi containment
- Antimicrobial molecules
- Fungal toxic metabolites