Dear Colleagues,

Cancer is a multifactorial disease driven by the accumulation of genetic mutations and epigenetic changes leading to cell malignancy. It has emerged that epigenetic modifications might precede gene mutations along tumorigenesis. Thus, they are unique targets for early detection and cancer treatment. Dissemination to distant organs and acquired resistance to conventional and targeted therapies are major cancer death causes. There is a strong unmet clinical need to identify novel therapeutic regimens to reduce cancer mortality.
This Special Issue on ”Cancer Chemoprevention” aims to contribute with original articles and reviews to the identification of chemopreventive agents that either delay or block the carcinogenesis of human tumors. The transition of this knowledge from bench to bedside might strongly reduce health care costs and improve the life quality of cancer patients.

Dr. Sabrina Strano
Guest Editor

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• chemopreventive agents
• epigenetic
• organoids and animal models
• cancer stem cells
• drug epurposing
• biomarkers for early detection
• cancer metabolism
• cancer microbiome