Special Issue "Molecular Mechanisms in Cancer Metastasis"
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: closed (31 March 2019).
Interests: fluorescent imaging; raman spectroscopy; nonlinear microscopy; optical biopsy; cancer metastasis; cancer diagnosis; osteoporosis; cartilage degeneration and regeneration
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Cancer metastasis is the leading cause of death globally. Even if diagnostics in primary cancer is developed, there is an urgent need to understand whether the cancer is localized or has already spread to other organs. The progressive growth of metastases is often resistant to conventional therapies. Understanding the characteristic differences in the aspect of molecular and cellular biology between primary cancer and metastatic lesions is essential for effective cancer treatment. This Special Issue, “Molecular Mechanisms in Cancer Metastasis”, is a part of the Section ‘’Molecular Pathology, Diagnostics, and Therapeutics’’ in IJMS. Our primary goals of cancer research are technical and instrumental development to address molecular mechanisms in cancer metastasis based on genomics, proteomics, and metabolomics in vivo and in vitro, and the establishment of a cancer metastasis model in experimental animals and molecular imaging techniques in cancer cells and their environment including other cells and extracellular matrix. Metastases can be characterized not only by cancer cells but also by environmental factors including immune cells, stroma cells, secretion vesicles, and the extracellular matrix, but to identify and detect cancer diagnostic biomarkers is still challenging. The aim of this Special Issue is to investigate and/or discuss morphological and molecular dynamics in cancer metastasis. We invite authors to submit full-length original articles and review papers for cancer research in both in vitro and in vivo assay of tumor tissues to reveal the metastasis process and to evaluate therapeutic effects of anti-cancer drugs and their drug delivery toward the clinical application of the technique.
Dr. Yusuke Oshima
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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- extracelluar matrix
- drug delivery
- cancer imaging
- animal models
- molecular-guided surgery
- optical biopsy
- cancer-specific probes