Special Issue "Gut Microbes and Gut Metabolites"
Deadline for manuscript submissions: closed (30 April 2021).
The scope of this special issue is to compile a series of original research papers and reviews that demonstrate a link between dietary metabolite products* and an improvement in human health indicators.
Interventions can provide microbes (probiotics) or foods/ supplements with components such as flavonoids, phenolic compounds or non-digestible carbohydrates (prebiotics) in the diet with the aim of effecting positive changes in the gut microbiota. Several general mechanisms have been established by which the gut bacteria or their major products (short chain fatty acids) can affect aspects of the host’s biology including the immune system, gut barrier function and energy metabolism. However, the mechanisms by which specific probiotics or prebiotics act are much less established.
Some of the microbial metabolite products - degradation products of polyphenols, complex carbohydrates, dietary protein and amino acids - and endogenous metabolites related to energy pathways (Krebs cycle, glycolysis, beta-oxidation) and those involved in digestion (bile acids) have the capacity to interact with the microbiome, leading potentially to a net positive balance in health or at least to a sustainable homeostasis.
In vivo and in vitro studies on host metabolism (lipid and energy pathways) and involvement of microbiota will be particularly welcome.
This special issue will offer experts in the field the opportunity to display the latest results in nutritional metabolomics/lipidomics and review the current developments while providing the readers with an exciting prospect of new possibilities in preventive medicine and precision nutrition research.
* phenolic compounds, short chain fatty acids, biogenic amines, etc.
Dr. Gwenaelle Le Gall
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- gut metabolites
- phenolic compounds
- short chain fatty acids