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Special Issue "Novel Targets for Treating Methamphetamine Use Disorder"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Toxicology".

Deadline for manuscript submissions: 28 February 2022.

Special Issue Editor

Prof. Dr. Karen Szumlinski
E-Mail Website
Guest Editor
Department of Psychological and Brain Sciences, University of California Santa Barbara, Santa Barbara, CA, USA
Interests: behavioral neuroscience; addiction; alcoholism; stimulants; opioids; animal models; anxiety; psychosis

Special Issue Information

Dear Colleagues,

Methamphetamine use disorder is a serious neuropsychiatric condition, characterized by intense drug-craving, compulsive drug-seeking and taking, and pronounced cognitive impairment.  In the wake of the opioid crisis and COVD-19 pandemic, methamphetamine-related deaths have risen to epidemic levels. This rise in methamphetamine-related deaths is concerning as currently, there exists no approved pharmacotherapy for treating methamphetamine use disorder and the available cognitive/behavioral therapies have proven relatively ineffective at reducing drug use and preventing relapse to the addicted state. Methamphetamine is well-characterized to impact monoaminergic neurotransmission in the brain and to do so via effects on plasmalemmal and vesicular transporters, as well as interactions with the TAAR1 receptor. In addition to affecting monoamine neurotransmission, methamphetamine is also reported to exert both short- and long-lasting effects upon several other neurotransmitters systems, as well as to perturb neuroimmune function.  This Special Topic will examine the neuropsychopharmacology of methamphetamine use disorder and focus on the latest developments from basic science, preclinical and clinical research regarding its pharmacotherapy. The discovery of a broad range of druggable targets to ameliorate the different symptoms of methamphetamine use disorder will inform biomedical strategies for predicting disease susceptibility, early and late intervention in the disease process, and promoting recovery.

Prof. Dr. Karen Szumlinski
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • methamphetamine use disorder
  • pharmacotherapy
  • addiction
  • relapse
  • vulnerability
  • drug self-administration
  • craving

Published Papers

This special issue is now open for submission.
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