Epigenetic Biomarkers in Nutrigenomics and Metabolomics

Dear Colleagues,

It is well known that environment–host–microbe interactions (which provide insight into nutritional status) can affect epigenetic mechanisms and shape human metabolism through the long-term regulation of gene expression. This is particularly crucial in the first 1000 days of life. Additionally, growing scientific evidence supports the idea that epigenetic signatures may affect nutrient metabolism and, consequently, health status. Accordingly, the onset and progression of metabolic diseases, such as obesity, type 2 diabetes, metabolic syndrome, fatty liver disease, and cardiovascular disorders, may involve epigenetic mechanisms. These include DNA methylation marks, covalent and non-covalent histone modifications, microRNA/non-coding RNA expression (in circulation or in tissues), telomere length, and imprinting phenomena. In this context, genomic, metagenomic, and nutrigenomic studies allow epigenetic biomarkers to be identified for predictive purposes and innovative intervention strategies to be designed for disease prevention or monitoring purposes by targeting the epigenome. Therefore, Nutrients welcomes the submission of manuscripts, either describing original research or reviewing scientific literature studies, on the topic of “Epigenetic Biomarkers in Nutrigenomics and Metabolomics”, highlighting recent advances in the discipline for the prevention, management, and prognosis of metabolic diseases under a precision nutrition scope.

Dr. Fermín Milagro
Dr. Omar Ramos-Lopez
Guest Editors

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• DNA methylation
• histone modifications
• miRNA/non-coding RNA
• imprinting
• nutrigenomics
• epigenetics
• metabolic diseases