Special Issue "Cardiovascular Diseases–A Focus on Atherosclerosis, Its Prophylaxis, Complications and Recent Advancements in Therapies"
Deadline for manuscript submissions: 31 July 2021.
Interests: atherosclerosis; hyperlipidemia; diabetes; arterial hypertension; obesity; clinical pharmacology; endocrinology
Despite tremendous advancements in the treatment of cardiovascular diseases and the advent of several new groups of drugs, the burden of morbidity and mortality resulting from atherosclerotic complications is still high. Atherosclerotic plaques are thought to be the essence of the disease, but in fact they are the mere final stage of numerous pathophysiologic processes involved in atherogenesis. These include hyperlipidaemia, diabetes, arterial hypertension, obesity, and many others. All these conditions are associated with an improper lifestyle and with extensive low-level inflammatory state and oxidative stress. The containment strategies recently introduced to control the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) pandemic have resulted in reduced physical activity and the worsening of the dietary habits.
Therefore, it is imperative to refocus on the importance of therapeutic lifestyle changes and propose novel preventive measures to counteract the consequences of the current and potentially future pandemic restrictions. Many drugs that are successfully used in the therapy of specific conditions have shown additional pleiotropic effects that are partly explained by their impact on cytokine signaling, their antioxidant capabilities, and their effects on micro-RNAs. Nevertheless, new therapies based on other mechanisms are needed. It also should be stressed that significant improvements have been achieved in the field of angioplasty, with novel stents and devices to improve the cardiac function, which is important to deal with the complications of atherosclerosis.
For this Special Issue, we urge authors to share their recent work on the epidemiology, prevention, and treatment of cardiovascular diseases, especially in the context of the coronavirus pandemic.
Dr. Łukasz Bułdak
Manuscript Submission Information
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- cardiovascular disease
- oxidative stress