Special Issue "Metabonomics in Gastroenterology and Hepatology"
Deadline for manuscript submissions: closed (31 March 2019).
Throughout the past two decades attempts have been made to reveal the true nature of a rang of puzzeling diseases within gastroenterology and hepatology using different kinds of omics. However, the dissection of genotype-phenotype relations have often been disappointing due to various downstream regulatory processes that take place from the genome to the metabolome, i.e. epigenome, epitranscriptome, epiproteome and the concomitant interactions with the exposome, e.g. nutrients, medication, and pollution, and the microbiome. Thus, the complexity of the network increases towards the metabolome and the read-out from the metabolome comprises information that is much closer to a meaningful patho/physiological phenotype.
With this special Issue of the International Journal of Molecular Sciences we wish to invite original papers and reviews that focus on metabonomics in gastroenterology and hepatology. The primary objective is to get insight into the pathophysiological molecular mechanisms at play in given disease phenotypes using metabonomics alone or in an integrative approach, i.e. in combination with other omics. However, papers on diagnostics, prognostics, biomarker identification, and treatment response biomarkers are welcome. Both human and animal models are appreciated.
Prof. Ole Haagen Nielsen
Dr. Jacob Tveiten Bjerrum
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- disease phenotype
- pathophysiology prognostics
- treatment response biomarkers