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Special Issue "Fate of Pancreatic Islets in Type 2 Diabetes"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Bioactives and Nutraceuticals".

Deadline for manuscript submissions: 31 August 2021.

Special Issue Editor

Dr. Shunichiro Asahara
E-Mail Website
Guest Editor
Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan
Interests: Diabetes; Endocrinology; Beta cell viability; Insulin signaling; mTORC1; Exosome

Special Issue Information

Dear Colleagues,

In the development of type 2 diabetes, the function and volume of pancreatic β-cells has been known as important factors. In particular, pancreatic β-cell mass is regulated by various factors. Recent studies revealed that dedifferentiation is associated with the regulation of pancreatic β-cell mass in addition to proliferation and apoptosis. This Special Issue of IJMS is focused on the molecular mechanisms of pancreatic β-cell fate, and aims to discuss underlying the mechanisms and downstream pathways involved in the pathogenesis of pancreatic β-cell failure. We welcome unique and creative basic research on the mechanisms of proliferation, apoptosis, transdifferentiation, neogenesis, and dedifferentiation of pancreatic β-cells. We look forward to your contributions.

Dr. Shunichiro Asahara
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • pancreatic β-cell
  • dedifferentiation
  • apoptosis
  • proliferation
  • neogenesis

Published Papers

This special issue is now open for submission.
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