Special Issue "Role of Stromal Cell Population in Myocardial Remodelling"
Deadline for manuscript submissions: 31 May 2021.
Interests: mechanism of multiorgan remodeling; heart pathogenesis; fibrosis; fibroblast; arrhythmia; conduction system; 3D cardiac models; systemic sclerosis; heart dysfunction
Special Issues and Collections in MDPI journals
Interests: myocarditis; inflammatory dilated cardiomyopathy; innate and adaptive immunity; mouse models of heart failure; myocardial inflammation; Wnt signaling
Stromal cells represent a heterogeneous cell population with connective tissue characteristics, displaying diverse differentiation potentials depending on the tissue and organ localization and playing a specific role in tissue homeostasis and remodeling. Cardiac stromal cells create the appropriate architecture for cardiomyocytes that ensures suitable cardiomyocyte alignment and function in homeostasis. During myocardial remodeling, stromal cells contribute to inflammatory and pro-fibrotic responses closely cross-talking with inflammatory and endothelial cells, indicating stromal cell populations as key objectives in targeted therapies. Nevertheless, the precise role of distinct cardiac stromal cell populations still remains not completely understood. Therefore, in this Special Issue, we encourage submission of manuscripts describing the subpopulations of cardiac stromal cells, their characteristic, function and role in homeostasis and remodeling mainly in cardiovascular and rheumatic diseases in in vitro or ex vivo setups including 3D culture models and in vivo models. We are highly interested in manuscripts reporting application of preclinical and clinical strategies targeting stromal cell activation or function. Likewise, studies on the specific signaling pathways responsible for activation and differentiation of cardiac stromal cells in these diseases and manuscripts describing cardiac immune cell–stromal cell cross-talk are within the scope of this Special Issue.
Dr. Przemyslaw Blyszczuk
Dr. Gabriela Kania
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Stromal cells, fibroblasts
- Heart failure in rheumatic diseases
- Cardiovascular diseases
- Myocardial inflammation
- Myocardial fibrosis
- Myocardial remodeling
- Animal models of heart failure
- 3D cardiac models