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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Erythrocyte Biology and Functions
edited by
submission deadline 30 Sep 2024 | Viewed by 64 | Submission Open
Keywords: erythrocyte; red blood cells; red blood functions; vascular function; blood bank storage
(This special issue belongs to the Section Molecular Biology)
Bioactive Compounds in Human Brain Structures and Diseases 2.0
edited by
submission deadline 30 Sep 2024 | Viewed by 64 | Submission Open
Keywords: brain; brain cancer; depression; neurodegenerative disorders; natural compounds
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Aspects of Cartilage Biology
edited by
submission deadline 30 Sep 2024 | Viewed by 62 | Submission Open
Keywords: cartilage biology; tissue regeneration; molecular mechanisms; chondrocytes; cartilage disorders; therapeutic interventions; biomaterials
(This special issue belongs to the Section Molecular Biology)
Dietary Bioactive Components in Inflammatory Bowel Disease, 2nd Edition submission deadline 30 Sep 2024 | Viewed by 62 | Submission Open
Keywords: IBD; dietary bioactive compounds; molecular mechanisms; health promotion; prevention; antioxidant; anti-inflammatory; nutritional support
(This special issue belongs to the Section Bioactives and Nutraceuticals)
Cellular and Molecular Mechanisms of Plant Responses to Light 2.0 submission deadline 30 Sep 2024 | Viewed by 61 | Submission Open
Keywords: celluar mechanism; light; molecular mechanism; plant growth; plant development; gene expression; primary and secondary metabolites; photomorphogenesis; photoperiod response; stress resistance; nutrient uptake
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular Research in Platelet Biology
edited by
submission deadline 30 Sep 2024 | Viewed by 60 | Submission Open
Keywords: platelets; aggregation; adhesion; thrombosis; hemostasis
(This special issue belongs to the Section Molecular Biology)
Neuroinflammation in the Pathogenesis of Alzheimer’s Disease and Related Dementias: 2nd Edition
edited by
submission deadline 30 Sep 2024 | Viewed by 60 | Submission Open
Keywords: Alzheimer’ s disease; neuroinflammation; drug development; microglia; astrocytes; cytokines; TREM2; risk factors; biomarkers
(This special issue belongs to the Section Molecular Immunology)
Latest Advances in Comparative Genomics submission deadline 30 Sep 2024 | Viewed by 60 | Submission Open
Keywords: genetics; genomics; evolution; phylogeny; sequencing; variation; conservation
(This special issue belongs to the Section Molecular Informatics)
Autophagy and Programmed Cell Death in Plants and Algae
edited by
submission deadline 30 Sep 2024 | Viewed by 59 | Submission Open
Keywords: algal autophagy and PCD; autophagy-related (Atg) genes and proteins; biotic and abiotic stresses; caspase-like proteases; crop plant improvement; macro-; micro-; and mega-autophagy; metacaspases; selective autophagy; signaling; vacuolar processing enzymes (VPEs)
(This special issue belongs to the Section Molecular Plant Sciences)
Molecular and Therapeutic Advanced Research in Prostate Cancer
edited by Carole Hélissey
submission deadline 30 Sep 2024 | Viewed by 58 | Submission Open
Keywords: cancer progression mechanisms; prostate cancer biomarkers; therapeutic targets; hormonal therapy updates; precision medicine in prostate cancer; detection advances; monitoring innovations; treatment resistance overcoming strategies
(This special issue belongs to the Section Molecular Oncology)
Design, Synthesis, and Bioapplications of Multifunctional Materials submission deadline 30 Sep 2024 | Viewed by 58 | Submission Open
Keywords: bioactivity; biodegradability; polymers; composite materials; (nano)structured materials; packaging; biological and biomedical materials
(This special issue belongs to the Section Materials Science)
Molecular Pathology and Molecular Pharmacology of Chronic Pain
edited by , Giulia Ottaviani and Katia Rupel
submission deadline 30 Sep 2024 | Viewed by 57 | Submission Open
Keywords: chronic pain; etiopathogenesis; molecular studies; pain management; therapeutic strategies; biomarkers; personalized medicine
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Insights into Multiple Sclerosis
edited by Yoshio Bando
submission deadline 30 Sep 2024 | Viewed by 57 | Submission Open
Keywords: multiple sclerosis; molecular mechanism; pathogenesis; biomarkers; therapeutic targets
(This special issue belongs to the Section Molecular Neurobiology)
Dopamine Neurons and the Genetic Pharmacology of Addiction: Unraveling Molecular Pathways submission deadline 30 Sep 2024 | Viewed by 57 | Submission Open
Keywords: dopamine; neurons; addiction; gene; personality traits; molecular mechanisms
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Pharmacology of Cardiovascular Disease, 2nd Edition
edited by
submission deadline 30 Sep 2024 | Viewed by 56 | Submission Open
Keywords: heart failure; internal medicine; cardiovascular disease; metabolic syndrome; pharmacology; cardiology; pharmacodynamics  
(This special issue belongs to the Section Molecular Pharmacology)
Pathogenesis and Molecular Treatment of Primary Liver Cancer
edited by
submission deadline 30 Sep 2024 | Viewed by 56 | Submission Open
Keywords: primary liver cancer; cholangiocarcinoma; hepatocellular carcinoma; hepatoblastoma; molecular pathogenesis; targeted therapies; anticancer drug
(This special issue belongs to the Section Molecular Oncology)
Current Advances and Perspectives in Microbial Genetics and Genomics
edited by and Lucila Saavedra
submission deadline 30 Sep 2024 | Viewed by 56 | Submission Open
Keywords: microbial genetics; genomics and metagenomics; gene regulation; microbe– host interactions; adaption and resistance mechanisms; microbial metabolism
(This special issue belongs to the Section Molecular Microbiology)
Bioinformatics in Neuro-Oncology: Latest Applications and Future Perspectives
edited by Marco M. Fontanella
submission deadline 30 Sep 2024 | Viewed by 56 | Submission Open
Keywords: artificial intelligence; machine leraning; deep learning; multiomics; neuro-oncology; liquid biopsy; pathobiology; genetics; molecular dynamics; proteomics
(This special issue belongs to the Section Molecular Informatics)
Proposal of a Special Issue on: Basic, Translational and Clinical Research on Dementia—2nd Edition
edited by , and Daniele Bano
submission deadline 30 Sep 2024 | Viewed by 55 | Submission Open
Keywords: dementia; Alzheimer’ s disease; amyloid-beta; tau protein
(This special issue belongs to the Section Molecular Neurobiology)
The Role of Choroid Plexus in Neurological Health
edited by
submission deadline 30 Sep 2024 | Viewed by 55 | Submission Open
Keywords: choroid plexus; cerebrospinal fluid; neurological health; blood– CSF barrier; central nervous system
(This special issue belongs to the Section Molecular Neurobiology)
Glutamatergic Signaling in the Nervous System
edited by
submission deadline 30 Sep 2024 | Viewed by 55 | Submission Open
Keywords: glutamate glutamine cycle; neurotoxicty; ferroptosis; hyperglutamatergic states; innovative pharmacological interventions
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Mechanism in DNA Replication and Repair
edited by Ryszard Maciejewski
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: DNA replication; genome stability; DNA repair mechanisms; mismatch repair mechanism; nucleotide excision repair; cancer risk
(This special issue belongs to the Section Molecular Genetics and Genomics)
Transcriptional Regulation in Plant Development: 2nd Edition submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: environmental stresses; plant development; vegetative development; plant physiology and biochemistry; transcriptional regulation; plant– environment interactions
(This special issue belongs to the Section Molecular Plant Sciences)
Cytotoxicity, Antioxidant and Anticancer Activity of Natural Products 2.0
edited by
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: natural products; anticancer activity; apoptosis; immunomodulation; free radicals; proliferation; phytomolecules; nanoparticles; drug delivery
(This special issue belongs to the Section Bioactives and Nutraceuticals)
The Role of Extracellular Vesicles in Inflammatory Diseases
edited by Kaushik Das
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: extracellular vesicles; inflammation; inflammatory diseases; pathogenesis
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Recent Advances in Molecular and Cellular Research in Ophthalmology
edited by Zala Lužnik Marzidovšek
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: eye disease; ophthalmology; molecular mechanisms; cellular mechanism; stem cell therapy; tissue engineering; gene therapy
(This special issue belongs to the Section Molecular Biology)
Exploring Molecular Mechanisms of Biomarkers in Cancer Treatment submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: biomarkers; cancer treatment; tumor microenvironment
(This special issue belongs to the Section Molecular Oncology)
New Insights Into the Antibacterial Effect of Nano- and Micro-Materials submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: antibacterial coatings; biomaterials; medical devices; antimicrobial resistance; nanomedicine
(This special issue belongs to the Section Materials Science)
Molecular and Cellular Perspectives on Wound Healing
edited by and Eugenia Carvalho
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: chronic wound healing; scarring; biomarkers; inflammation; angiogenesis; infection; extracellular matrix; biomaterials; tissue regeneration; therapeutic targets; innovative therapies
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Advances in Artificial Reproduction and Female Health: From Molecular Diagnosis to the Treatment of Gynecological Diseases
edited by Liselotte Mettler
submission deadline 30 Sep 2024 | Viewed by 54 | Submission Open
Keywords: gynecological diseases; molecular diagnostic technologies; reproductive medicine; artificial reproduction; gynecological endocrinology; adnexal tumors; genital and breast cancer; urogynecology; uterine fibroids
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Gut Microbiome: Key Player in Human Health and Disease
edited by
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: bacteriome; virome; gastrointestinal physiology; gut-associated lymphoid tissue; akkermansia muciniphila; probiotics; gut– brain axis; gut– liver axis; gut– renal axis
(This special issue belongs to the Section Molecular Microbiology)
Innovative Molecular Strategies in Biomedical Research and Therapeutics: Harnessing Peptides, Bioprinting and Nanotechnology
edited by
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: bioprinting; organ-on-chip; venom-derived therapeutics; 3D in vitro models; skeletal muscle models; toxic peptides; peptide expression; nanoparticles in medicine; protein and peptide drug delivery; peptide-based biomaterials; self-assembled hydrogels; molecular therapeutics; nanotechnology in drug delivery; regenerative medicine; tissue engineering
(This special issue belongs to the Section Materials Science)
Pigment Cells: From Biology to Medicine
edited by
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: melanin; melanocyte; melanogenesis; melanoma; melanosome; neuromelanin; photoprotection; oxidative stress; phototoxicity; pigmentation disorders; drug– melanin complexes; skin cancer; UV radiation; retinal pigment epithelium
(This special issue belongs to the Section Molecular Biology)
Antibodies and Aptamers Used as Molecular Recognition Components in Sensing Platforms
edited by
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: aptasensors; immunosensors; electrochemical systems; optical systems; molecular recognition
(This special issue belongs to the Section Molecular Biology)
Cellular Senescence and the Senescence-Associated Secretory Phenotype (SASP) in Age-Related Diseases
edited by Jordi Olloquequi
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: cellular senescence; senescence-associated secretory phenotype (SASP); age-related diseases; atherosclerosis; chronic obstructive pulmonary disease (COPD); type 2 diabetes mellitus (T2DM); non-alcoholic fatty liver disease (NAFLD); Alzheimer’ s disease (AD); inflammation; therapeutic targets
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Molecular Mechanisms of Phytochemicals in Antioxidation, Antimicrobial, and Cytoprotective Properties
edited by
submission deadline 30 Sep 2024 | Viewed by 53 | Submission Open
Keywords: phytochemicals; antioxidant; antimicrobial; cytoprotective; in vitro screening; in vivo evaluation
(This special issue belongs to the Section Bioactives and Nutraceuticals)
RNA Biology: Unraveling the Complex Interplay between Proteins and RNAs in Gene Expression and Regulation
edited by
submission deadline 30 Sep 2024 | Viewed by 52 | Submission Open
Keywords: RNA biology; protein– RNA interplay; gene expression; post-transcriptional modifications; non-coding RNAs
(This special issue belongs to the Section Molecular Biology)
Revealing New Molecular Mechanisms in Medicinal Chemistry
edited by Margaret E. Olson
submission deadline 30 Sep 2024 | Viewed by 52 | Submission Open
Keywords: pharmacology; pharmacokinetics; covalent; competitive; uncompetitive; agonist; antagonist; drug development; mechanism of action
(This special issue belongs to the Section Molecular Pharmacology)
Deciphering the Dynamics: Exploring Tumor Evolution in Cancer
edited by
submission deadline 30 Sep 2024 | Viewed by 52 | Submission Open
Keywords: genetic mutations; clonal evolution; tumor heterogeneity; metastasis; therapeutic resistance
(This special issue belongs to the Section Molecular Oncology)
Molecular Research of Ocular Pathologies, 2nd Edition submission deadline 30 Sep 2024 | Viewed by 52 | Submission Open
Keywords: ocular pathologies; dry eye; glaucoma; retinal diseases; oxidative stress; inflammation; molecular treatments; molecular biomarkers  
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Drought-Stress Induced Physiological and Molecular Changes in Plants 3.0 submission deadline 30 Sep 2024 | Viewed by 52 | Submission Open
Keywords: drought stress; water stress; signal transduction; genes; transcripts; and proteins; primary and secondary metabolism; phytohormones; antioxidants; reactive oxygen species; photosynthetic apparatus; photosynthesis
(This special issue belongs to the Section Molecular Plant Sciences)
Metabolomic Profiling in Prenatal Health Research
edited by Onur Turkoglu
submission deadline 30 Sep 2024 | Viewed by 51 | Submission Open
Keywords: metabolomics; biomarker; obstetrics; prenatal health; maternal health; fetal health; perinatology; high risk; pregnancy
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Reproduction and Cancer: Cell-Cell Interaction and Signal Transduction
edited by Mónica H Vazquez-Levin
submission deadline 30 Sep 2024 | Viewed by 51 | Submission Open
Keywords: fertilization; embryogenesis; implantation; placentation; tumorigenesis; tumor progression; metastasis; cell-cell adhesion; cell signaling; invasion; angiogenesis; hormone regulation; metabolic reprogramming; epigenetics; immune response; spermatozoa; oocyte; embryo
(This special issue belongs to the Section Molecular Oncology)
Oxidative Stress and Inflammation in the Tissue Repair—Pathways and Biotechnologies
edited by Reggiani Vilela Gonçalves and Rômulo Dias Novaes
submission deadline 30 Sep 2024 | Viewed by 51 | Submission Open
Keywords: oxidative stress; inflammasome; cytokines; angiogenesis; remodeling; molecular pathways; apoptotic alterations; diabetes; tissue repair  
(This special issue belongs to the Section Biochemistry)
Advances in Enzyme Inhibitors: Mechanisms, Applications, and Future Perspectives submission deadline 30 Sep 2024 | Viewed by 51 | Submission Open
Keywords: enzyme inhibitors; drug design; drug discovery; drug therapy; resistance mechanisms; cancer; drug delivery systems; biocatalysts; enzymes in industrial applications
(This special issue belongs to the Section Biochemistry)
Pathology and Treatment of Extracellular Vesicles in Neurodegenerative Diseases
edited by Daisy Sproviero
submission deadline 30 Sep 2024 | Viewed by 50 | Submission Open
Keywords: extracellular vesicles; nervous system; neurodegenerative diseases; exosomes
(This special issue belongs to the Section Molecular Neurobiology)
Metabolic Pathways in Cancer Cells
edited by
submission deadline 30 Sep 2024 | Viewed by 50 | Submission Open
Keywords: tumor microenvironment; metabolism; cancer; metabolic reprogramming; Warburg effect  
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
Molecular and Cellular Mechanisms in Mood Disorders
edited by Sara Palumbo
submission deadline 30 Sep 2024 | Viewed by 49 | Submission Open
Keywords: neurobiology of mood disorders; intracellular signalling in mood disorders; neurophysiological alterations in mood disorders; genetic risk of mood disorders; pharmacological targets for mood disorders
(This special issue belongs to the Section Molecular Neurobiology)
Molecular Informatics and Genomics of Alzheimer’s Disease
edited by
submission deadline 30 Sep 2024 | Viewed by 49 | Submission Open
Keywords: Alzheimer’ s disease; bioinformatics; brain; single cell RNASeq; genomics
(This special issue belongs to the Section Molecular Neurobiology)
Recent Advances in Biomedical Application of Polymeric Micelles submission deadline 30 Sep 2024 | Viewed by 49 | Submission Open
Keywords: polymeric micelles; nanomedicine; drug delivery; amphiphilic compounds; therapeutic applications
(This special issue belongs to the Section Macromolecules)
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