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Nutrients
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The Role of Nutrients, Probiotics and Nutraceuticals in Cognitive Function...
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The Role of Nutrients, Probiotics and Nutraceuticals in Cognitive Function across the Lifespan

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 5 August 2024 | Viewed by 3698

Special Issue Editor

Prof. Dr. Con Stough

E-Mail Website
Guest Editor
Centre for Human Psychopharmacology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia
Interests: cognition; cognitive ageing; nutraceuticals; probiotics; improving cognitive performance across the lifespan

Special Issue Information

Dear Colleagues,

In this Special Issue, we aim to focus on theoretical and empirical contributions to the understanding of the role of nutrients, herbal extracts, probiotics, and other non-pharmaceutical substances in improving cognitive function across the human lifespan. This volume is focused on providing contributions that help us to understand the mechanisms by which these substances improve cognitive function, as well as empirical studies including animal and human clinical trials. Systematic reviews and meta-analyses are also welcomed if they provide important information on whether a nutrient, nutraceutical or other non-pharmaceutical substance improves cognitive function. Novel ways to describe and report cognitive function are welcomed. In addition, we also welcome contributions that discuss the role of age in identifying compounds that improve cognitive function and biological targets across different ages for cognitive enhancement. Cognitive enhancement may include studies that aim to ameliorate some type of cognitive deficit or that improve cognitive function in already healthy individuals, including nootropic studies into the presence of non-pharmaceutical substances in patient groups.

Prof. Dr. Con Stough
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrients
  • nutraceuticals
  • herbal extracts
  • cognition
  • cognitive health
  • probiotics
  • memory

Published Papers (2 papers)

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Research

18 pages, 798 KiB  
Article
Comparison of Eating Habits, Body Composition and Densitometric Parameters between Subjects with Normal Cognitive Function and Mild Cognitive Impairment: An Observational Study
by Małgorzata Jamka, Maria Chrobot, Natalia Jaworska, Jan Brylak, Aleksandra Makarewicz-Bukowska, Joanna Popek, Adrianna Janicka and Jarosław Walkowiak
Nutrients 2024, 16(5), 644; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16050644 - 25 Feb 2024
Viewed by 813
Abstract
The role of nutrition in the ageing process of the brain is pivotal. Therefore, the study aimed to compare eating habits, body composition and densitometric parameters between subjects with normal cognitive function (NCF) and mild cognitive impairment (MCI). A total of 95 subjects [...] Read more.
The role of nutrition in the ageing process of the brain is pivotal. Therefore, the study aimed to compare eating habits, body composition and densitometric parameters between subjects with normal cognitive function (NCF) and mild cognitive impairment (MCI). A total of 95 subjects with NCF (74% of women) and 95 individuals with MCI (77% of women) aged 50–70 years were studied. Densitometric parameters were evaluated using dual-energy X-ray absorptiometry methods. Eating habits were assessed using the food frequency questionnaire and 3-day diary records, and advanced glycation end products (AGEs) intake was calculated. Significant differences between groups were detected for the %fat in the right arm (NCF vs. MCI: 38.4 (30.4–46.8) vs. 43.5 (35.5–49.2)%, p = 0.0407). Moreover, the MCI group had a significantly lower intake of calcium (p = 0.0010), phosphor (p = 0.0411), vitamins B2 (p = 0.0138) and B12 (p = 0.0024) compared to the NCF group, with both groups also differing in the frequency of butter (p = 0.0191) and fermented milk beverages (p = 0.0398) intake. Analysis restricted to women showed significant differences between groups in right arm %fat, VAT mass, calcium, vitamins B2, B12, butter and fermented milk products intake, while in men, differences were detected in the intake of calcium, iodine, vitamin B1, water and AGEs. In conclusion, subjects with NCF and MCI have comparable densitometric variables but differ significantly in some body composition parameters and the intake of some food groups and nutrients. Full article
(This article belongs to the Special Issue The Role of Nutrients, Probiotics and Nutraceuticals in Cognitive Function across the Lifespan)
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14 pages, 909 KiB  
Article
Formulated Palmitoylethanolamide Supplementation Improves Parameters of Cognitive Function and BDNF Levels in Young, Healthy Adults: A Randomised Cross-Over Trial
by Nadia Kim, Brenda Parolin, Derek Renshaw, Sanjoy K. Deb and Mohammed Gulrez Zariwala
Nutrients 2024, 16(4), 489; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16040489 - 08 Feb 2024
Viewed by 2596
Abstract
Background: Palmitoylethanolamide (PEA) is an endocannabinoid-like lipid mediator which is naturally produced in the body and found in certain foods. The aim of this study was to assess the effect of a bioavailable formulated form of PEA (Levagen+®) on serum BDNF [...] Read more.
Background: Palmitoylethanolamide (PEA) is an endocannabinoid-like lipid mediator which is naturally produced in the body and found in certain foods. The aim of this study was to assess the effect of a bioavailable formulated form of PEA (Levagen+®) on serum BDNF levels and parameters of cognitive function in healthy adults. Methods: A randomised double-blinded placebo-controlled cross-over trial was implemented to measure the effects of a 6-week 700 mg/day course of formulated PEA supplementation versus a placebo. Participants (n = 39) completed pre- and post-assessments of a lab-based cognitive test. Serum samples were collected to measure BDNF concentrations using an immunoassay. Results: A significant increase in serum BDNF levels was found following PEA supplementation compared with the placebo (p = 0. 0057, d = 0.62). The cognition test battery demonstrated improved memory with PEA supplementation through better first success (p = 0.142, d = 0.54) and fewer errors (p = 0.0287; d = −0.47) on the Paired Associates Learning test. Conclusion: This was the first study to report a direct beneficial effect of Levagen+® PEA supplementation on memory improvement as well as corresponding increases in circulating neurotrophic marker levels. This suggests that formulated PEA holds promise as an innovative and practical intervention for cognitive health enhancement. Full article
(This article belongs to the Special Issue The Role of Nutrients, Probiotics and Nutraceuticals in Cognitive Function across the Lifespan)
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