The Effects of Nutritional Intake during Pregnancy on Maternal and Offspring Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: 15 May 2024 | Viewed by 513

Special Issue Editors


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Guest Editor
Department of Food and Nutrition, Faculty of Human Sciences and Design, Japan Women’s University, 2-8-1 Mejirodai, Bunkyo-ku, Tokyo 112-8681, Japan
Interests: developmental origin of health and disease; fetal growth; placental growth; noncommunicable disease; genetic risks; epigenetics; nutrient profile; nutrition and health science

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Co-Guest Editor
School of Medicine, Department of Obstetrics and Gynecology (Obstetrics) (Shinanomachi), Keio University, Tokyo, Japan
Interests: life science; obstetrics and gynecology; gestational diabetes; preterm birth; genome/epigenome; ultrasound; pregnancy after radical trachelectomy/conization; DOHaD

Special Issue Information

Dear Colleagues,

During pregnancy, the mother’s physiological adaptations and changes in nutritional requirements are necessary to accommodate placental formation and intense fetal growth. Inadequate maternal intake of macronutrients, micronutrients, and dietary fibers and/or excessive intake of energy may increase the risk of pregnancy complications and subsequent development of noncommunicable diseases for both mother and offspring. In fetal growth, appropriate weight gain, as well as the normal functional development of the brain, metabolic organs, and other tissues, is crucial. Recently, it has been shown that metabolites derived from maternal gastrointestinal microbiota play a vital role in fetal development through the regulation of immunity and metabolism. In other words, diet has an important influence not only as a nutritional element for the formation of the placenta and fetus but also in maintaining the preferable compositions of the gastrointestinal microbiota. A comprehensive understanding of the importance of diet during pregnancy and proper assessment of diet quality and quantity is necessary to promote maternal and offspring health.

This Special Issue aims to update our knowledge on this topic and to inform practice. We invite all researchers, scholars, dieticians, nutrition specialists, and clinicians involved in this field to submit original research articles, clinical studies, and review articles to this Special Issue.

Prof. Dr. Noriko Sato
Dr. Yoshifumi Kasuga
Guest Editors

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Keywords

  • developmental origin of health and disease (DOHaD)
  • placental programming
  • fetal growth
  • gestational weight gain
  • gestational diabetes
  • maternal diet
  • microbiome and microbiota
  • infant development

Published Papers (1 paper)

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Review

20 pages, 648 KiB  
Review
Amino Acids during Pregnancy and Offspring Cardiovascular–Kidney–Metabolic Health
by You-Lin Tain and Chien-Ning Hsu
Nutrients 2024, 16(9), 1263; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16091263 - 24 Apr 2024
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Abstract
Amino acids are essential for normal pregnancy and fetal development. Disruptions in maternal amino acid metabolism have been associated with various adult diseases later in life, a phenomenon referred to as the developmental origins of health and disease (DOHaD). In this review, we [...] Read more.
Amino acids are essential for normal pregnancy and fetal development. Disruptions in maternal amino acid metabolism have been associated with various adult diseases later in life, a phenomenon referred to as the developmental origins of health and disease (DOHaD). In this review, we examine the recent evidence highlighting the significant impact of amino acids on fetal programming, their influence on the modulation of gut microbiota, and their repercussions on offspring outcomes, particularly in the context of cardiovascular–kidney–metabolic (CKM) syndrome. Furthermore, we delve into experimental studies that have unveiled the protective effects of therapies targeting amino acids. These interventions have demonstrated the potential to reprogram traits associated with CKM in offspring. The discussion encompasses the challenges of translating the findings from animal studies to clinical applications, emphasizing the complexity of this process. Additionally, we propose potential solutions to overcome these challenges. Ultimately, as we move forward, future research endeavors should aim to pinpoint the most effective amino-acid-targeted therapies, determining the optimal dosage and mode of administration. This exploration is essential for maximizing the reprogramming effects, ultimately contributing to the enhancement of cardiovascular–kidney–metabolic health in offspring. Full article
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