Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
9.0
5.9
Journals
Nutrients
Special Issues
Nutritional Intervention in Mental Health
nutrients-logo
Submit to Nutrients Review for Nutrients Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Nutritional Intervention in Mental Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition and Public Health".

Deadline for manuscript submissions: closed (25 April 2024) | Viewed by 7537

Special Issue Editors

Prof. Dr. Hans-Willi Clement

E-Mail Website
Guest Editor
Center for Mental Illness, University Medical Center Freiburg, D-79104 Freiburg, Germany
Interests: nutrition; psychiatry; neurology; child; adolescent
Special Issues, Collections and Topics in MDPI journals
Dr. Annabel Müller-Stierlin

E-Mail Website
Co-Guest Editor
Department of Psychiatry and Psychotherapy II, Ulm University, 89070 Ulm, Germany
Interests: mental health; healthcare services research; community-based care; integrated care; nutrition
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nutrition supports our bodies with what is needed for growth and development. The bricks of life, represented by macronutrients and micronutrients, not only have effects on growth and functionality, but they also play important roles in the neuropsychiatric development of children and adolescents and maintain functionality in adult daily life. The dietary behaviour of neuropsychiatric patients is poorly understood, and it is thought that it may favor the disease rather then the healing process, or vice versa. Patients with mental health problems might need a personalized composition of their daily meals. Special diets might be helpful, with the ketogenic diet for patients with medication for refractory epilepsy providing an important example. The role of the microbiome in the context of neuropsychiatric disorders may also be important, as recent research results have begun to demonstrate. The most recent discoveries made and research carried out in this field will hopefully help patients with neuropsychiatric diseases.

This Special Issue will focus on the relationship between nutrition and neuropsychiatric diseases/development as a promising field of research, new discoveries, and nutritional help.

Prof. Dr. Hans-Willi Clement
Dr. Annabel Müller-Stierlin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nutrition
  • psychiatry
  • neurology
  • child
  • adolescent
  • adult
  • depression
  • schizophrenia
  • ADHD
  • microbiome
  • epilepsy

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

13 pages, 2768 KiB  
Article
Differential Alterations of Expression of the Serotoninergic System Genes and Mood-Related Behavior by Consumption of Aspartame or Potassium Acesulfame in Rats
by José Jaime Martínez-Magaña, Alma Delia Genis-Mendoza, Ileana Gallegos-Silva, María Lilia López-Narváez, Isela Esther Juárez-Rojop, Juan C. Diaz-Zagoya, Carlos Alfonso Tovilla-Zárate, Thelma Beatriz González-Castro, Humberto Nicolini and Anayelly Solis-Medina
Nutrients 2024, 16(4), 490; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16040490 - 08 Feb 2024
Viewed by 1557
Abstract
The use of aspartame (ASP) and potassium acesulfame (ACK) to reduce weight gain is growing; however, contradictory effects in body mass index control and neurobiological alterations resulting from artificial sweeteners consumption have been reported. This study aimed to evaluate the impact of the [...] Read more.
The use of aspartame (ASP) and potassium acesulfame (ACK) to reduce weight gain is growing; however, contradictory effects in body mass index control and neurobiological alterations resulting from artificial sweeteners consumption have been reported. This study aimed to evaluate the impact of the chronic consumption of ASP and ACK on mood-related behavior and the brain expression of serotonin genes in male Wistar rats. Mood-related behaviors were evaluated using the swim-forced test and defensive burying at two time points: 45 days (juvenile) and 95 days (adult) postweaning. Additionally, the mRNA expression of three serotoninergic genes (Slc6a4, Htr1a, and Htr2c) was measured in the brain areas (prefrontal cortex, hippocampus, and hypothalamus) involved in controlling mood-related behaviors. In terms of mood-related behaviors, rats consuming ACK exhibited anxiety-like behavior only during the juvenile stage. In contrast, rats consuming ASP showed a reduction in depressive-like behavior during the juvenile stage but an increase in the adult stage. The expression of Slc6a4 mRNA increased in the hippocampus of rats consuming artificial sweeteners during the juvenile stage. In the adult stage, there was an upregulation in the relative expression of Slc6a4 and Htr1a in the hypothalamus, while Htr2c expression decreased in the hippocampus of rats consuming ASP. Chronic consumption of ASP and ACK appears to have differential effects during neurodevelopmental stages in mood-related behavior, potentially mediated by alterations in serotoninergic gene expression. Full article
(This article belongs to the Special Issue Nutritional Intervention in Mental Health)
►▼ Show Figures

Graphical abstract

17 pages, 9220 KiB  
Article
Novel Psychopharmacological Herbs Relieve Behavioral Abnormalities and Hippocampal Dysfunctions in an Animal Model of Post-Traumatic Stress Disorder
by Hee Ra Park, Mudan Cai and Eun Jin Yang
Nutrients 2023, 15(17), 3815; https://0-doi-org.brum.beds.ac.uk/10.3390/nu15173815 - 31 Aug 2023
Viewed by 1340
Abstract
Post-traumatic stress disorder (PTSD) is an anxiety disorder caused by traumatic or frightening events, with intensified anxiety, fear memories, and cognitive impairment caused by a dysfunctional hippocampus. Owing to its complex phenotype, currently prescribed treatments for PTSD are limited. This study investigated the [...] Read more.
Post-traumatic stress disorder (PTSD) is an anxiety disorder caused by traumatic or frightening events, with intensified anxiety, fear memories, and cognitive impairment caused by a dysfunctional hippocampus. Owing to its complex phenotype, currently prescribed treatments for PTSD are limited. This study investigated the psychopharmacological effects of novel COMBINATION herbal medicines on the hippocampus of a PTSD murine model induced by combining single prolonged stress (SPS) and foot shock (FS). We designed a novel herbal formula extract (HFE) from Chaenomeles sinensis, Glycyrrhiza uralensis, and Atractylodes macrocephala. SPS+FS mice were administered HFE (500 and 1000 mg/kg) once daily for 14 days. The effects of HFE of HFE on the hippocampus were analyzed using behavioral tests, immunostaining, Golgi staining, and Western blotting. HFE alleviated anxiety-like behavior and fear response, improved short-term memory, and restored hippocampal dysfunction, including hippocampal neurogenesis alteration and aberrant migration and hyperactivation of dentate granule cells in SPS+FS mice. HFE increased phosphorylation of the Kv4.2 potassium channel, extracellular signal-regulated kinase, and cAMP response element-binding protein, which were reduced in the hippocampus of SPS+FS mice. Therefore, our study suggests HFE as a potential therapeutic drug for PTSD by improving behavioral impairment and hippocampal dysfunction and regulating Kv4.2 potassium channel-related pathways in the hippocampus. Full article
(This article belongs to the Special Issue Nutritional Intervention in Mental Health)
►▼ Show Figures

Graphical abstract

Other

Jump to: Research

24 pages, 627 KiB  
Systematic Review
The Microbiota–Gut–Brain Axis in Metabolic Syndrome and Sleep Disorders: A Systematic Review
by Adriano dos Santos and Serena Galiè
Nutrients 2024, 16(3), 390; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16030390 - 29 Jan 2024
Cited by 1 | Viewed by 4057
Abstract
Background: Over recent decades, a growing body of evidence has emerged linking the composition of the gut microbiota to sleep regulation. Interestingly, the prevalence of sleep disorders is commonly related to cardiometabolic comorbidities such as diabetes, impaired lipid metabolism, and metabolic syndrome (MetS). [...] Read more.
Background: Over recent decades, a growing body of evidence has emerged linking the composition of the gut microbiota to sleep regulation. Interestingly, the prevalence of sleep disorders is commonly related to cardiometabolic comorbidities such as diabetes, impaired lipid metabolism, and metabolic syndrome (MetS). In this complex scenario, the role of the gut–brain axis as the main communicating pathway between gut microbiota and sleep regulation pathways in the brain reveals some common host–microbial biomarkers in both sleep disturbances and MetS. As the biological mechanisms behind this complex interacting network of neuroendocrine, immune, and metabolic pathways are not fully understood yet, the present systematic review aims to describe common microbial features between these two unrelated chronic conditions. Results: This systematic review highlights a total of 36 articles associating the gut microbial signature with MetS or sleep disorders. Specific emphasis is given to studies evaluating the effect of dietary patterns, dietary supplementation, and probiotics on MetS or sleep disturbances. Conclusions: Dietary choices promote microbial composition and metabolites, causing both the amelioration and impairment of MetS and sleep homeostasis. Full article
(This article belongs to the Special Issue Nutritional Intervention in Mental Health)
►▼ Show Figures

Graphical abstract

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop