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Special Issue "Molecular Research in Allergic Diseases 2.0"

A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Endocrinology and Metabolism".

Deadline for manuscript submissions: 30 September 2021.

Special Issue Editor

Prof. Dr. Fiorentina Roviezzo
E-Mail Website
Guest Editor
Department of Pharmacy, School of Medicine, University of Naples Federico II, Naples, Italy
Interests: pulmonary inflammation, sphingolipid, airway inflammation
Special Issues and Collections in MDPI journals

Special Issue Information

Dear Colleagues,

Over the last years bioactive lipids have emerged as clinically-relevant mediators of allergic disease pathophysiology. Compelling evidence suggests the importance of lipid mediators in the development of asthma, allergic rhinitis, atopic dermatitis, anaphylaxis, and food allergy. Lipids play key roles in cell signaling events, influencing physiologic (bronchial tone) and immune mechanisms (degranulation, chemotaxis, and sensitization) in allergic diseases. Lipids act through several cellular mechanisms such as the formation of structural support platforms (lipid rafts) for receptor signaling complexes, the activation of a diverse family of G-protein coupled receptors, and the mediation of intracellular signaling cascades by acting as second messengers. An increased understanding of these critical bioactive molecules will drive future innovations in treating atopy in its many forms. This Special Issue aims to shed light on and further the understanding of some of these intricate signaling mechanisms in allergic diseases. Specifically, we propose to explore and discuss the following points: (1) lipid synthesis pathways and signaling in atopic disease pathology; (2) the development of allergic disease treatments targeting lipid mediator pathways

Prof. Fiorentina Roviezzo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. There is an Article Processing Charge (APC) for publication in this open access journal. For details about the APC please see here. Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • atopy
  • asthma
  • immune inflammation
  • sphingolipid
  • leukotrienes
  • anaphylaxis
  • therapeutic targets
  • food allergy

Published Papers

This special issue is now open for submission.
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