Advances in Molecular Research of Oral Diseases and Related Biomaterials
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Materials Science".
Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 13976
Special Issue Editor
Interests: oral medicine; periodontology; oral diseases; biomaterials; oral biomarkers
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In dentistry and oral and maxillofacial surgery, the development of molecular, cellular, and pharmaceutical research is currently a major field of research and education, with a considerable impact on the daily clinical practice and the evolution of therapeutic strategies.
The mechanisms underlying the initiation and progression of oral diseases are very complex and not entirely understood. The maintenance of oral health depends mainly on the homeostasis between the oral microbiome and host immune systems, and its disruption is a major event in the initiation of oral disease. Host microbial homeostasis in the oral cavity could be disrupted by ecological, genetic, and epigenetic factors, as well as by subverting the host immune system by some keystone pathogens. A dysregulated immune response is considered to be the major cause of periodontal tissue damage. The immune response is driven by different immune cell types, tissue-resident cells, and numerous pro- and anti-inflammatory cytokines. Understanding the exact mechanisms involved in the progression and control of the immune response is crucially important for the development of new strategies of periodontitis treatment and prevention.
This Special Issue welcomes in vitro, animal, and pre-clinical studies and reviews on the cellular and molecular mechanisms involved in the maintenance of oral host–microbe homeostasis and the regulation of the immune response during oral health and disease. Moreover, studies on biomaterials applied in the oral and maxillofacial field are also accepted.
Prof. Gaetano Isola
Guest Editor
Manuscript Submission Information
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Keywords
- oral diseases
- periodontal diseases
- dental biomaterials
- serum markers
- salivary markers
- oral health
- biofilm
- host response
- miRNA