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Nutrients
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Influence of Antenatal Nutrition on the Outcome of Pregnancy
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Influence of Antenatal Nutrition on the Outcome of Pregnancy

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".

Deadline for manuscript submissions: 5 September 2024 | Viewed by 2582

Special Issue Editor

Dr. Ann Anderson Berry

E-Mail Website
Guest Editor
Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE 68198, USA
Interests: neonatal and perinatal nutrition; fat soluble vitamins; neonatology; prematurity; vitamin D; vitamin A; vitamin E; carotenoids; omega 3 specialized proresolving mediators
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Nutrition is an essential issue at every age, and evidence supports the premise that the first 1000 days of life are the most critical for establishing health and development. In order to develop properly in utero, fetuses need proper nutrients, and mothers need to be replete in macro and micronutrients. This provision of nutrients can be complicated by maternal chronic illness as well as complications of pregnancy such as diabetes, hyperemesis, or hypertensive disorders of pregnancy. In the past decade, rapid expansion in nutrition scientific fields and, in particular, in the amount of population-based epidemiological evidence has helped to clarify the role of the perinatal diet in the prevention, treatment, and control of morbidity, as well as premature mortality for both mothers and infants. We welcome rigorous research on topics such as dietary components as well as interventions used to modify their impact and delivery of evidenced based interventions.

This Special Issue will include manuscripts that focus on perinatal nutrition, diet, nutritional treatment, and/or weight status in relation to maternal and neonatal outcomes, preterm delivery prevention, chronic disease prevention and control, as well as maternal symptom management. This Special Issue will bring together international scientific nutrition experts’ cutting-edge research, providing clinicians, scientists, and public health professionals state-of-the-art evidence to advance practice, science and policy.

Dr. Ann Anderson Berry
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (2 papers)

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Research

15 pages, 702 KiB  
Article
Omega-3 Polyunsaturated Fatty Acid Levels in Maternal and Cord Plasma Are Associated with Maternal Socioeconomic Status
by Alexandra Hergenrader, Matthew VanOrmer, Rebecca Slotkowski, Maranda Thompson, Alyssa Freeman, Olivia Paetz, Sarah Sweeney, Lauren Wegner, Khadijjta Ali, Nicole Bender, Ridhi Chaudhary, Melissa Thoene, Corrine Hanson and Ann Anderson-Berry
Nutrients 2023, 15(20), 4432; https://0-doi-org.brum.beds.ac.uk/10.3390/nu15204432 - 19 Oct 2023
Cited by 1 | Viewed by 961
Abstract
Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) play a crucial role in fetal growth and neurodevelopment, while omega-6 (n-6) PUFAs have been associated with adverse pregnancy outcomes. Previous studies have demonstrated that socioeconomic status (SES) influences dietary intake of n [...] Read more.
Omega-3 (n-3) polyunsaturated fatty acids (PUFAs) play a crucial role in fetal growth and neurodevelopment, while omega-6 (n-6) PUFAs have been associated with adverse pregnancy outcomes. Previous studies have demonstrated that socioeconomic status (SES) influences dietary intake of n-3 and n-6 PUFAs, but few studies have evaluated the association between maternal and cord plasma biomarkers of PUFAs and socioeconomic markers. An IRB-approved study enrolled mother–infant pairs (n = 55) at the time of delivery. Maternal and cord plasma PUFA concentrations were analyzed using gas chromatography. Markers of SES were obtained from validated surveys and maternal medical records. Mann–Whitney U tests and linear regression models were utilized for statistical analysis. Maternal eicosapentaenoic acid (EPA) (p = 0.02), cord EPA (p = 0.04), and total cord n-3 PUFA concentrations (p = 0.04) were significantly higher in college-educated mothers vs. mothers with less than a college education after adjustment for relevant confounders. Insurance type and household income were not significantly associated with n-3 or n-6 PUFA plasma concentrations after adjustment. Our findings suggest that mothers with lower educational status may be at risk of lower plasma concentrations of n-3 PUFAs at delivery, which could confer increased susceptibility to adverse pregnancy and birth outcomes. Full article
(This article belongs to the Special Issue Influence of Antenatal Nutrition on the Outcome of Pregnancy)
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13 pages, 507 KiB  
Article
Folic Acid Supplementation during Pregnancy and Its Association with Telomere Length in Children at Four Years: Results from the INMA Birth Cohort Study
by Fanny Petermann-Rocha, Desirée Valera-Gran, Daniel Prieto-Botella, Dries S Martens, Sandra Gonzalez-Palacios, Isolina Riaño-Galán, Mario Murcia, Amaia Irizar, Jordi Julvez, Loreto Santa-Marina, Adonina Tardón, Jordi Sunyer, Jesús Vioque, Tim Nawrot and Eva-María Navarrete-Muñoz
Nutrients 2023, 15(19), 4303; https://0-doi-org.brum.beds.ac.uk/10.3390/nu15194303 - 09 Oct 2023
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Abstract
This study examined the association between folic acid supplements (FAs) during different periods of pregnancy and offspring telomere length (TL) at age four in 666 children from the INMA study. FAs were self-reported using food-structured questionnaires during three periods of pregnancy (the first [...] Read more.
This study examined the association between folic acid supplements (FAs) during different periods of pregnancy and offspring telomere length (TL) at age four in 666 children from the INMA study. FAs were self-reported using food-structured questionnaires during three periods of pregnancy (the first three months of pregnancy, from month fourth onward, and the whole pregnancy). For each period, the average daily dosage of FAs was categorised into (i) <400 μg/d, (ii) ≥400 to 999 μg/d, (iii) ≥1000 to 4999 μg/d, and (iv) ≥5000 μg/d. Leucocyte TL at age four was measured using quantitative PCR methods. Multiple robust linear log-level regression models were used to report the % difference among FA categories. During the first period, and compared with children whose mothers were classified in the reference group (<400 μg/d), children whose mothers took higher dosages of FAs showed shorter TL at age four (≥5000 μg/d). When the first and the second periods were mutually adjusted, children whose mothers self-reported ≥5000 μg/d during the first period of pregnancy had a statistically significant shorter TL than their counterparts (% difference: −7.28% [95% CI: −14.42 to −0.13]). Similar trends were observed for the whole period of pregnancy. When the analysis was stratified by sex, the association was more evident in boys (% difference: −13.5% [95% CI: −23.0 to −4.04]), whereas no association was observed in girls. This study suggests that high dosages of FAs in the first pregnancy period may be associated with a shorter TL in children at age four, particularly among boys. Further studies should confirm these results. Full article
(This article belongs to the Special Issue Influence of Antenatal Nutrition on the Outcome of Pregnancy)
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