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Dear Colleagues,

Chronic diseases (previously called non-communicable diseases) have been the world’s number one cause of death for several decades. These diseases are highly interconnected, such that an initial chronic disease often leads to additional comorbid conditions as well as polypharmacy during the aging process. This pattern results in significant burdens on individuals and their families, as well as increased medical needs across the patient’s life course. Chronic diseases can involve virtually every tissue, organ, or system of the body. Fortunately, dietary approaches offer a tremendous opportunity to prevent individual chronic diseases and/or blunt the pattern of comorbidities, polypharmacy, and reduced quality of life.

This Special Issue of Nutrients, “Dietary Approaches and Prevention of Chronic Diseases”, welcomes original research articles as well as reviews. Topics can include: 1) any chronic disease(s), 2) any dietary approach from among the journal’s scope, and 3) any target system/disease category (e.g., neurological, immunological, metabolic, reproductive, endocrine, gastrointestinal, musculoskeletal, or cardiovascular) as well as the microbiome. As a reminder, the journal’s scope includes the subjects of: macronutrients, micronutrients, essential nutrients, bioactive nutrients, nutrient requirements, nutrient sources, human nutrition aspects, functional foods, nutraceuticals (e.g., prebiotics and probiotics), health claims, public health, diet-related disorders, metabolic syndrome, malnutrition, nutritional supplements, sport nutrition, nutritional status and body composition, bariatric surgery, sarcopenia, nutritional physiology, and nutrigenomics. Importantly, the focus should be on prevention of an initial chronic disease and/or subsequent spread to comorbid diseases with increased risk of polypharmacy. Both broad public health strategies as well as personalized approaches will be welcomed. The Special Issue’s goal is to demonstrate the utility of specific dietary approaches for reducing the prevalence of chronic diseases.

Prof. Dr. Rodney R. Dietert
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

dietary factors
prevention
chronic diseases
neurobehavioral conditions
metabolic diseases
allergic/autoimmune diseases
cardiovascular
comorbidity
polypharmacy
microbial and host metabolism

Published Papers (2 papers)

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Editorial

Jump to: Review

4 pages, 206 KiB

Open AccessEditorial

Dietary Approaches from Moms, Farms, and Nature to Overcome Chronic Diseases and the Pharmacracy

by Rodney R. Dietert

Nutrients 2023, 15(18), 3965; https://0-doi-org.brum.beds.ac.uk/10.3390/nu15183965 - 14 Sep 2023

Viewed by 1121

Abstract

Chronic diseases, previously called noncommunicable diseases, are the leading cause of global death and were recently estimated by the World Health Organization to account for 74% of all deaths [...] Full article

(This article belongs to the Special Issue Dietary Approaches and Prevention of Chronic Diseases)

Review

Jump to: Editorial

23 pages, 1308 KiB

Open AccessReview

Sickle Cell Disease Update: New Treatments and Challenging Nutritional Interventions

by Victoria Bell, Theodoros Varzakas, Theodora Psaltopoulou and Tito Fernandes

Nutrients 2024, 16(2), 258; https://0-doi-org.brum.beds.ac.uk/10.3390/nu16020258 - 15 Jan 2024

Cited by 1 | Viewed by 2852

Abstract

Sickle cell disease (SCD), a distinctive and often overlooked illness in the 21st century, is a congenital blood disorder characterized by considerable phenotypic diversity. It comprises a group of disorders, with sickle cell anemia (SCA) being the most prevalent and serious genotype. Although there have been some systematic reviews of global data, worldwide statistics regarding SCD prevalence, morbidity, and mortality remain scarce. In developed countries with a lower number of sickle cell patients, cutting-edge technologies have led to the development of new treatments. However, in developing settings where sickle cell disease (SCD) is more prevalent, medical management, rather than a cure, still relies on the use of hydroxyurea, blood transfusions, and analgesics. This is a disease that affects red blood cells, consequently affecting most organs in diverse manners. We discuss its etiology and the advent of new technologies, but the aim of this study is to understand the various types of nutrition-related studies involving individuals suffering from SCD, particularly in Africa. The interplay of the environment, food, gut microbiota, along with their respective genomes collectively known as the gut microbiome, and host metabolism is responsible for mediating host metabolic phenotypes and modulating gut microbiota. In addition, it serves the purpose of providing essential nutrients. Moreover, it engages in direct interactions with host homeostasis and the immune system, as well as indirect interactions via metabolites. Nutrition interventions and nutritional care are mechanisms for addressing increased nutrient expenditures and are important aspects of supportive management for patients with SCD. Underprivileged areas in Sub-Saharan Africa should be accompanied by efforts to define and promote of the nutritional aspects of SCD. Their importance is key to maintaining well-being and quality of life, especially because new technologies and products remain limited, while the use of native medicinal plant resources is acknowledged. Full article

(This article belongs to the Special Issue Dietary Approaches and Prevention of Chronic Diseases)

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