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Rice Bran for Human Health
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Rice Bran for Human Health

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Phytochemicals and Human Health".

Deadline for manuscript submissions: closed (30 September 2020) | Viewed by 8654

Special Issue Editor

Prof. Dr. Hitoshi Shirakawa

E-Mail Website
Guest Editor
Laboratory of Nutrition, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
Interests: vitamin; life style related disease; transcription regulation; chromatin; rice bran
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Rice bran is a byproduct of the rice milling process and contains various functional ingredients for the promotion of human health—e.g., thiamine as an anti-beriberi factor was identified more than one century ago. It is well known that a major fraction of rice bran contains lipid and highly unsaponifiable components, such as tocotrienol, gamma-oryzanol, ferulic acid, and beta-sitosterol. These ingredients show several beneficial functions, including antidiabetic, anti-hypertensive, and anti-cardiovascular disease. Additionally, rice bran also has amino acids and dietary fiber. In this Special Issue, we focus on the insights of rice bran research regarding its properties in the promotion of human health and prevention of diseases. Submission of original research articles or reviews related to the following (non-exhaustive) topics is encouraged.

Prevention and amelioration of life-style related diseases by rice bran, processed rice bran (enzyme-treated or fermented, etc.) and its ingredients in studies on humans;

Mechanisms of rice bran, processed rice bran (enzyme-treated or fermented, etc.) and their ingredients on prevention and amelioration of lifestyle-related disease in disease-model animals and cell-based research.

Prof. Dr. Hitoshi Shirakawa
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • rice bran
  • antidiabetes
  • anti-hypertense
  • anti-cardiovascular disease
  • lifestyle-related disease

Published Papers (2 papers)

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Research

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14 pages, 3329 KiB  
Article
Supplementation with Fermented Rice Bran Attenuates Muscle Atrophy in a Diabetic Rat Model
by Tubagus Bahtiar Rusbana, Afifah Zahra Agista, Wahyu Dwi Saputra, Yusuke Ohsaki, Kouichi Watanabe, Ardy Ardiansyah, Slamet Budijanto, Takuya Koseki, Hisashi Aso, Michio Komai and Hitoshi Shirakawa
Nutrients 2020, 12(8), 2409; https://0-doi-org.brum.beds.ac.uk/10.3390/nu12082409 - 12 Aug 2020
Cited by 12 | Viewed by 4475
Abstract
Fermented rice bran (FRB), a prospective supplement, has been proven to ameliorate certain medical conditions. However, its nutraceutical effect on muscle atrophy has never been investigated. The present study aimed to evaluate the effect of FRB on muscle atrophy in a streptozotocin (STZ)-induced [...] Read more.
Fermented rice bran (FRB), a prospective supplement, has been proven to ameliorate certain medical conditions. However, its nutraceutical effect on muscle atrophy has never been investigated. The present study aimed to evaluate the effect of FRB on muscle atrophy in a streptozotocin (STZ)-induced diabetic rat model. Three groups of Sprague-Dawley rats, namely the control, STZ, and FRB groups, were treated as follows. The diabetic groups (STZ and FRB) were injected intraperitoneally with STZ (40 mg/kg BW), whereas the control group was injected with the vehicle. The STZ and control groups were fed the AIN93M diet, and the FRB group was fed 10% of FRB based on the AIN93M diet. The diabetic groups had reduced muscle size compared to the control group; however, these changes were alleviated in the FRB group. Moreover, the FRB group had a significantly lower expression of FBXO32/Atrogin-1 and TRIM63/MuRF1 (p < 0.05) due to blocked NF-κB activation. In conclusion, the anti-inflammatory effect of FRB may be beneficial for ameliorating muscle atrophy in diabetic conditions. Full article
(This article belongs to the Special Issue Rice Bran for Human Health)
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Review

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11 pages, 1814 KiB  
Review
Anti-Hypertensive Effects of Peptides Derived from Rice Bran Protein
by Naohisa Shobako and Kousaku Ohinata
Nutrients 2020, 12(10), 3060; https://0-doi-org.brum.beds.ac.uk/10.3390/nu12103060 - 07 Oct 2020
Cited by 12 | Viewed by 3677
Abstract
Hypertension is one of the major risk factors for arteriosclerosis. Anti-hypertensive peptides derived from animal proteins, such as milk, eggs and fish, are well studied. Anti-hypertensive peptides have also been identified from plant proteins such as soybeans. Rice bran, a byproduct of white [...] Read more.
Hypertension is one of the major risk factors for arteriosclerosis. Anti-hypertensive peptides derived from animal proteins, such as milk, eggs and fish, are well studied. Anti-hypertensive peptides have also been identified from plant proteins such as soybeans. Rice bran, a byproduct of white rice polishing, is rich in protein and its high protein efficiency ratio is well known. This review discusses the anti-hypertensive peptides identified from rice bran protein and their mechanisms. In addition, we describe protease-digested rice bran from which functional peptides have not been isolated. Full article
(This article belongs to the Special Issue Rice Bran for Human Health)
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