Dear Colleagues,

Extracellular vesicles are a heterogeneous group of cell-derived membranous structures comprising exosomes and microvesicles, originating from the endosomal system or which come off from the plasma membrane. All cells are able of secreting various types of extracellular vesicles, and this process is conserved throughout the evolution process from bacteria to humans. They have been evidenced in biological fluids and are involved in several physiological and pathological cells processes. Also, extracellular vesicles can be are considered as an supplementary machinery involved in intercellular communication, in any case much remains unidentified regarding the origin, biogenesis, secretion, targeting and fate of these vesicles.

The objective of this special issue is to know this rapidly growing research field of extracellular vesicles, conveying together a range of basic and clinical researchers focusing on issues of biologic actions of vesicles and their clinical potential in the human development and in the discovery of diagnostic biomarkers and therapeutics.

Prof. Dr. Oriana Trubiani
Dr. Francesca Diomede
Dr. Jacopo Pizzicanella
Guest Editors

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• extracellular vesicles
• miRNAs
• proteins
• DNA
• RNA
• human development
• biomarkers
• diagnosis
• therapy